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2.2.4Scaling Up

Blood Vessels

5 min read 9 parts Lesson 11 of 16 1 quiz

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Section 1 of 9The circulatory system

Blood vessels: artery, capillary, vein (blood flow)
Blood vessels structure and function: artery, capillary, vein
Double circulation diagram (heart, lungs, body)
Artery vs vein cross-section (tunica layers)
Double circulation in humans

Humans have a double circulatory system.

1
In the pulmonary circuit, blood goes from the heart to the lungs to pick up oxygen, then back to the heart.
2
In the systemic circuit, the heart pumps the oxygenated blood to the body and deoxygenated blood returns.
3
The blood passes through the heart twice in each full circuit,
  • which allows it to be pumped at a higher pressure to the body after having been slowed in the lung capillaries.
4
Three kinds of vessel carry the blood: arteries, veins and capillaries.

Section 2 of 9Arteries

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Arteries carry blood away from the heart, at high pressure.

1
Their walls are thick and contain elastic fibres and muscle.
2
The elastic fibres stretch as blood surges out of the heart and recoil afterward,
  • which evens out the flow, and the muscle can narrow or widen the vessel.
3
The lumen is small compared with the wall thickness.
4
In the body, arteries carry oxygenated blood, with the exception of the pulmonary artery to the lungs.
5
The pulse you feel in your wrist is the stretching of arteries each heartbeat.
6
Main arteries include the aorta (to the body), the pulmonary artery (to the lungs) and the coronary arteries (supplying the heart muscle itself).

Section 3 of 9Veins and capillaries

Capillary: wall one cell thick, red blood cells
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Capillary wall one cell thick with endothelial cell
Thin capillary wall and red blood cells
Thin capillary wall and red blood cells

Veins carry blood back to the heart at low pressure. They have thinner walls with less muscle and elastic tissue, a wide lumen to reduce resistance to flow, and valves that stop the backflow of blood. Muscle movement around the veins squeezes the blood along. Veins generally carry deoxygenated blood except for the pulmonary vein.

Capillaries are the smallest vessels, where exchange takes place between blood and the body cells. Their walls are one cell thick, giving a short diffusion distance. They are very narrow and form dense networks, giving a large total surface area, and they are leaky so some plasma can pass out to form tissue fluid.

Section 4 of 9Comparison table

FeatureArteryVeinCapillary
Direction of flowAway from heartTowards heartBetween arteries and veins
PressureHighLowFalling
WallThick, elastic and muscularThinOne cell thick
LumenNarrowWideVery narrow
ValvesNoYesNo

Section 5 of 9Interpreting data and links

Data questions often give blood pressure or velocity values for each vessel type.

1
Pressure is highest in the aorta and falls steadily through the arteries, capillaries and veins; it is lowest in the veins close to the heart.
2
Total cross-sectional area is greatest in the capillaries, so blood slows there, giving more time for exchange.
3
A pulse is visible only in arteries.
4
If a vessel is damaged, bright red blood that spurts indicates an artery; dark blood that flows steadily indicates a vein.

Blood vessels link to heart disease

  • fatty deposits narrow coronary arteries, reducing blood and oxygen supplied to the heart muscle, which can cause a heart attack.
  • Stents hold arteries open and statins reduce cholesterol.

Section 6 of 9Blood vessels in health and disease

Blood vessel sequence from artery through capillary network to vein
Artery, arteriole, capillaries, venule and vein structure compared
Blood Vessels
Blood Vessels
Blood Vessel Types
Blood Vessels
Coronary Heart Disease
heart blood flow
heart blood flow
Risk Factors for Coronary Heart Disease
Capillary with one-cell-thick wall and red blood cells in lumen
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Control of Blood Glucose
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Sickle Cell Blood-Flow Blockage
Coronary artery disease and heart attack
Artery vs. Vein — Structural Comparison
Normal vs narrowed artery (plaque build-up)

The structure of each vessel explains how it can go wrong.

1
In coronary heart disease, fatty material builds up in the walls of the coronary arteries and narrows the lumen.
2
Less blood reaches the heart muscle, which receives less oxygen and glucose for respiration; a complete blockage by a clot causes a heart attack.
3
Treatments include statins to lower blood cholesterol, stents (small wire mesh tubes) to hold the artery open,
  • and bypass surgery, using a vein taken from the leg to carry blood around the blockage.
4
Lifestyle risk factors include smoking, a diet rich in saturated fat, high blood pressure and inactivity.

Varicose veins appear when the valves fail and blood pools in the veins.

Blood vessels in health and disease
In a blood test or blood-pressure measurement, the first figure is the pressure when the heart contracts and the second when it relaxes.
Compare the vessels by how well each is suited to its job: the artery withstands pressure, the capillary enables exchange,
  • and the vein returns blood with a low resistance to flow.

In calculations of heart rate from a pulse, count the beats in a set time and scale up: 18 beats in 15 seconds is 72 beats per minute.

Section 7 of 9Exam-style questions

The Composition of Blood — Animated
The Composition of Blood — Animated
The Composition of Blood — Animated
Capillary structure
  1. Explain how the structure of an artery is related to its function. [3]3 marks

  2. Give two ways a capillary is adapted for exchange. [2]2 marks

  3. The blood pressure in the aorta is 120 mmHg and in a vein is 10 mmHg. Calculate how many times greater the pressure in the aorta is and suggest why veins need valves. [3]3 marks

Section 8 of 9Key terms

TermMeaning
ArteryA vessel carrying blood away from the heart at high pressure.
VeinA vessel carrying blood towards the heart, with valves.
CapillaryA very small vessel with walls one cell thick where exchange occurs.
LumenThe space inside a blood vessel.
ValveA flap that prevents the backflow of blood.
Double circulatory systemA system in which blood passes through the heart twice in one circuit of the body.
AortaThe main artery leaving the left ventricle.

Section 9 of 9Exam technique

1
Saying all arteries carry oxygenated blood and all veins deoxygenated; the pulmonary vessels are the exceptions.
2
Saying that veins have a thick wall; arteries do.
3
Stating that blood pressure is high in capillaries; it has fallen by that stage.
4
Writing "capillaries have thin walls to let blood through" instead of explaining that thin walls allow diffusion.
5
Mixing up the direction of flowarteries away, veins to the heart.
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