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BIOLOGY · Stage 9 · Chapter 13: Variation and Natural Selection

Biology 13.3 Environmental change and natural selection — Antibiotic Resistance

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13.3 Environmental change and natural selection — Antibiotic Resistance — Alhussan International Academy — Biology (Stages 7–9) notes: Explain how environmental change drives natural selection and how bacteria evolve resistance to antibiotics.Adaptation — natural selection produc…

  • Climate change
  • Variation helps
  • Original environment
  • After the change
  • Life cycles
  • Linked species

Section 1 of 7Environmental change

  • Adaptation
    • natural selection produces populations that survive in their environment, and changes in that environment affect the organisms living there.
    • Date palms and olive trees may survive in low temperatures but will not bear fruit.
  • Climate change
    • many environments are getting hotter and drier, some are getting wetter, winters may be colder or end sooner, and rains are failing.
  • Variation helps
    • every population contains variation, and individuals that were different may have characteristics suited to the new conditions,
    • so the population can survive.
  • Survival
    • living organisms must adapt or they will not survive, and natural selection changes populations to fit the environment.

Section 2 of 7Drought-adapted plants

  • Original environment
    • with 25 mm of rain in the growing season most plants produce 7 flowers and an average of 28 seeds,
    • but some produce 5 flowers or 3 flowers with fewer seeds.
  • After the change
    • when global warming cuts rainfall to 15 mm many plants die or fail to set seed.
    • The variants with fewer flowers and seeds cope better with less water and reproduce successfully.
  • Result
    • as dry conditions continue, natural selection acts until most of the population is the drought-adapted variation.

Section 3 of 7Interdependence and extreme events

  • Life cycles
    • plant and animal life cycles are often linked through feeding relationships,
    • so patterns of reproduction change and food supply can fail if the environment changes.
    • Many organisms in hot, dry regions depend on rains to reproduce, so delayed or failed rains threaten whole populations.
  • Linked species
    • if one species changes by natural selection, other interdependent species must also adapt or die out.
  • Kestrels
    • they are small birds of prey widespread in Africa, Asia and Europe, with a diet that varies with where they live.
    • They reproduce successfully when average temperature rises, because those best able to cope breed successfully.
    • Extreme droughts damage kestrel populations, because there are no adaptations for severe, unpredictable drought.
  • Speed of change
    • natural selection has always allowed adaptation, but climate change is now happening very fast.

Section 4 of 7Antibiotics and bacteria

  • Antibiotics = medicines that kill bacteria or stop them growing, without harming human cells.
    • They treat bacterial infections such as pneumonia but do not work on viruses, so they are no use against colds or flu.
  • Fast reproduction
    • bacteria sometimes divide every 20 minutes, so a population can evolve rapidly.

Section 5 of 7How resistance develops

  1. Variation caused by mutation occurs in a population,
    • and a random mutation produces a resistant bacterium, for example by changing the target of the drug.
  2. The antibiotic kills most non-resistant bacteria, but the resistant one survives.
  3. The survivor reproduces with little competition and passes on the resistance allele.
  4. The population of resistant bacteria increases, so the antibiotic no longer works well.
  • Selection pressure
    • this is natural selection with the antibiotic as the selection pressure.
  • Plasmids
    • bacteria can pass resistance genes to other bacteria, even of different species, in small rings of DNA.

Section 6 of 7Superbugs

  • MRSA (methicillin-resistant Staphylococcus aureus)
    • a well-known resistant bacterium spread in hospitals.
  • Tuberculosis
    • multidrug-resistant forms are a global concern.
  • Danger
    • infections by resistant bacteria are harder, more expensive and sometimes impossible to treat.
    • The World Health Organization regards antibiotic resistance as a major threat.
    • Routine operations and cancer treatments depend on effective antibiotics.

Section 7 of 7Reducing resistance

  • Doctors should prescribe antibiotics only when necessary and not for viral infections.
  • Patients must complete the whole course so that all the bacteria are killed.
  • Farmers should reduce routine use of antibiotics in animal feed.
  • Hospitals should use strict hygiene, such as hand washing and isolating infected patients.
  • Scientists develop new antibiotics and drug combinations, though this is difficult and costly.
Normal evolutionAntibiotic resistance
Takes thousands of years in large animalsOccurs in years because bacteria reproduce quickly
Selection by climate, predatorsSelection by the antibiotic

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