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1.2.41 · Cell Structure

Prokaryotic v Eukaryotic Cells — Cambridge AS & A Level Biology 9700 Revision Notes & Topical Questions

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1.2.4 Prokaryotic v Eukaryotic Cells — CAMBRIDGE AS & A LEVEL BIOLOGY 9700 — REVISION NOTES notes: Describe the structure of prokaryotic cells and compare them with eukaryotic cells.Genetic material — circular DNA free in the cytoplasm, not packaged with proteins.No membrane-boun…

  • No membrane-bound organelles
  • Organisation
  • Pili and flagella
  • Microvilli
  • Respiration
  • Microtubule

Part 1 of 6Features of prokaryotic cells

Genetic material
  • Genetic material circular DNA free in the cytoplasm, not packaged with proteins.
No membrane-bound organelles
  • No membrane-bound organelles there is no nucleus or mitochondria.
Size
  • Size usually 1–5 µm, many times smaller than eukaryotic cells.
Ribosomes
  • Ribosomes smaller 70S ribosomes.
Cell wall
  • Cell wall made of peptidoglycan.
Organisation
  • Organisation always unicellular.

Part 2 of 6Extra prokaryotic structures

Extra prokaryotic structures
Plasmids
  • Plasmids small circular DNA molecules in many bacteria.
Capsule
  • Capsule a slime layer outside some cell walls.
Pili and flagella
  • Pili and flagella attachment and movement.

Part 3 of 6Eukaryotic cell features

Genetic material
  • Genetic material linear chromosomes in a nucleus, associated with histone proteins.
Organelles
  • Organelles multiple membrane-bound organelles such as a nucleus, mitochondria and chloroplasts.
Ribosomes
  • Ribosomes larger 80S ribosomes.
Cell wall
  • Cell wall cellulose in plants and chitin in fungi.
Size
  • Size up to 100 µm across.
Organisation
  • Organisation can form multicellular organisms.

Part 4 of 6Comparison table

FeatureProkaryotesEukaryotes
Size0.5–5 µmUp to 100 µm
Genetic materialCircular chromosome, no proteinsLinear chromosomes with histones in nucleus
Cell divisionBinary fission, no spindleMitosis or meiosis with spindle fibres
Ribosomes70S80S
OrganellesNo membrane-bound organellesMany membrane-bound organelles
Cell wallPeptidoglycanCellulose or chitin

Part 5 of 6More from the specification

More from the specification
Endoplasmic Reticulum and Vesicular Transport
  • Rough endoplasmic reticulum synthesizes proteins destined for secretion,
  • which bud off in transport vesicles that fuse with the Golgi body for post-translational modification and sorting.
The Golgi Apparatus and Secretion
  • The Golgi body modifies proteins and lipids, packaging them into secretory vesicles or lysosomes that travel to the cell surface membrane for exocytosis of substances.
Microvilli and Absorption Surface Area
  • In specialized animal epithelial cells,
  • such as those lining the small intestine and kidney nephrons, the cell surface membrane folds into microvilli to substantially expand the surface area for rapid absorption of nutrients.
Non-Cellular Viruses vs. Living Animal and Bacterial Cells
  • Viruses are acellular infectious entities lacking metabolic machinery, cytoplasm,
  • and organelles;
    • unlike living animal cells that generate metabolic energy via cellular respiration, viruses replicate only within host cells.
Endoplasmic Reticulum and Vesicular Transport
  • Rough endoplasmic reticulum synthesizes proteins destined for secretion,
  • which bud off in transport vesicles that fuse with the Golgi body for post-translational modification and sorting.
The Golgi Apparatus and Secretion
  • The Golgi body modifies proteins and lipids, packaging them into secretory vesicles or lysosomes that travel to the cell surface membrane for exocytosis of substances.
Microvilli and Absorption Surface Area
  • In specialized animal epithelial cells,
  • such as those lining the small intestine and kidney nephrons, the cell surface membrane folds into microvilli to substantially expand the surface area for rapid absorption of nutrients.
Non-Cellular Viruses vs. Living Animal and Bacterial Cells
  • Viruses are acellular infectious entities lacking metabolic machinery, cytoplasm,
  • and organelles;
    • unlike living animal cells that generate metabolic energy via cellular respiration, viruses replicate only within host cells.
Centriole
  • A microtubule structure organising the spindle in animal cells.
Animal cell
  • A cell with a nucleus, cytoplasm, cell membrane and mitochondria but no cell wall, chloroplasts or large vacuole.
Endoplasmic reticulum
  • Rough and smooth (lipids, detoxification).
    • (ribosomes, proteins)
Nuclear envelope
  • The double membrane around the nucleus, with pores.
Electron micrograph
  • A photograph taken through an electron microscope.
Aerobic respiration
  • Respiration that uses oxygen to release a relatively large amount of energy.
Permanent vacuole
  • Sap-filled space that keeps a plant cell firm.
Vesicle
  • A small membrane-bound sac that moves materials within a cell or to the plasma membrane.
Microvilli
  • Tiny folds on the surface of villus cells.
Respiration
  • Chemical reactions in cells that break down nutrient molecules and release energy for metabolism.
Microtubule
  • Hollow protein filament used for support and transport.
Vacuole
  • Membrane-bound store; the plant central vacuole maintains turgor.
Micrograph
  • A photograph taken through a microscope.

Part 6 of 6More on this topic

  • Organisation
    • prokaryotes are always unicellular, whereas eukaryotes can be multicellular.

Key terms

TermMeaning
ProkaryoteA cell with no nucleus and no membrane-bound organelles.
EukaryoteA cell with a nucleus and membrane-bound organelles.
PeptidoglycanThe cell wall material of bacteria.
Binary fissionDivision of a prokaryotic cell into two without a spindle.
PlasmidA small circular DNA molecule in bacteria.
70S ribosomeThe smaller ribosome type in prokaryotes, mitochondria and chloroplasts.

Avoid these mistakes

1
Saying prokaryotes have no DNA — they have DNA that is not in a nucleus.
2
Saying all cell walls contain cellulose — bacteria use peptidoglycan.
3
Saying prokaryotes divide by mitosis — they divide by binary fission.
4
Saying mitochondria are prokaryotic cells — they are organelles with 70S ribosomes.

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