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9.1.59 · Gas Exchange

Structures and Functions of the Gas Exchange System — Cambridge AS & A Level Biology 9700 Revision Notes & Topical Questions

5 min read 10 parts Lesson 7 of 9 Unit quiz

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9.1.5 Structures and Functions of the Gas Exchange System — CAMBRIDGE AS & A LEVEL BIOLOGY 9700 — REVISION NOTES notes: Explain how the structures of the airways and alveoli suit their functions, using Fick's law.Three jobs — carry air to the alveoli, protect the delicate exchang…

  • Mucus escalator
  • Warming and humidifying
  • Smooth muscle
  • Elastic fibres
  • Very large surface area
  • Thin walls

Part 1 of 8Overview of functions

  • Three jobs
    • carry air to the alveoli, protect the delicate exchange surface from damage and infection, and allow efficient diffusion between air and blood.

Part 2 of 8Main function of each part

StructureMain function
Trachea and bronchiConduct air; clean and warm it; resist collapse
BronchiolesDistribute air to alveoli; adjust airflow
AlveoliGas exchange
Capillary networkCarries blood to and from alveoli and maintains the gradient

Part 3 of 8Trachea and bronchi

Cartilage
  • Cartilage it prevents collapse.
Mucus escalator
  • Mucus escalator goblet cells and mucous glands secrete mucus rich in glycoproteins that traps bacteria, spores and dust.
  • Cilia beat in a coordinated way to move the mucus to the pharynx, where it is swallowed.
Warming and humidifying
  • Warming and humidifying capillaries beneath the lining warm the air, and mucus and moisture humidify it.
  • Warm, moist air does not damage the alveoli or dry the exchange surface.

Part 4 of 8Bronchioles

Smooth muscle
  • Smooth muscle contraction narrows the lumen to restrict irritant particles or gases, and relaxation widens it so air flows faster in exercise.
Elastic fibres
  • Elastic fibres they let the walls return to their original diameter.
Branching
  • Branching total cross-sectional area increases, so air slows towards the alveoli, giving time for diffusion.

Part 5 of 8The alveolus as an exchange surface

Very large surface area
  • Very large surface area there are roughly 300 to 500 million alveoli in the two lungs, giving roughly 70 m2.
Thin walls
  • Thin walls squamous epithelium and capillary endothelium are each one cell thick, giving a diffusion distance below 1 micrometre.
Dense capillary network
  • Dense capillary network blood flow removes oxygen and brings carbon dioxide, keeping gradients steep.
  • Red cells are squeezed in single file, slowing them and bringing them close to the wall.
  • The capillary is only 3 to 4 micrometres wide, so there is time for exchange.
Moist lining
  • Moist lining oxygen dissolves in the water film before diffusing;
    • surfactant stops the film collapsing the alveolus.
Elastic fibres
  • Elastic fibres the alveolus stretches to take in air and recoils to expel it.
Ventilation
  • Ventilation it maintains high oxygen and low carbon dioxide in the alveolus compared with the blood.

Part 6 of 8Fick's law and efficiency

Fick's law
  • Fick's law rate of diffusion is proportional to ÷ diffusion distance.
    • (surface area × concentration difference)
Use
  • Use the alveolar adaptations raise the numerator or reduce the denominator.
Fibrosis
  • Fibrosis it thickens the wall, increasing the distance.
Emphysema
  • Emphysema it destroys walls, reducing the surface area.
Pulmonary oedema
  • Pulmonary oedema fluid fills the alveoli, increasing the distance.
Asthma
  • Asthma narrowed bronchioles lower airflow.

Part 7 of 8Other exchange surfaces

Other exchange surfaces
Four shared features
  • Four shared features a large surface area, a short diffusion distance, a mechanism to maintain a gradient and a moist surface.
Fish gill
  • Fish gill many thin lamellae on each filament give a large area.
  • Blood and water flow in opposite directions (counter-current), so equilibrium is never reached.
Insect
  • Insect air passes through spiracles into tracheae and tracheoles that reach almost every cell.
  • Fluid in the tracheole ends is withdrawn during activity to shorten the diffusion path.
Leaf
  • Leaf air spaces and stomata, with spongy mesophyll giving a large internal surface area.
Cost of a moist surface
  • Cost of a moist surface mammals lose water vapour when breathing out.

Part 8 of 8More from the specification

More from the specification
Epithelial lining of the respiratory tract
  • Ciliated pseudostratified columnar epithelium with mucus-secreting goblet cells lines the trachea and bronchi, trapping inhaled particulate matter and microorganisms.
Alveolar wall ultrastructure
  • Transmission electron micrographs reveal that alveolar walls consist of squamous epithelial cells and extracellular elastic fibres, providing an extremely thin diffusion pathway.
    • (<1 micrometre)
Smooth muscle and cartilage in airway regulation
  • C-shaped hyaline cartilage rings prevent tracheal collapse during inhalation,
  • while bronchial smooth muscle contracts or relaxes to adjust airflow resistance.
Tissue
  • A group of cells of similar structure that perform the same function.
Photomicrograph
  • A photograph taken through a light microscope.
Micrograph
  • A photograph taken through a microscope.
Microorganism
  • A living organism so small that it can only be seen clearly with a microscope.
Electron micrograph
  • A photograph taken through an electron microscope.

Key terms

TermMeaning
Fick's lawDiffusion rate is proportional to surface area × concentration difference ÷ diffusion distance.
Mucus escalatorMucus swept upward by cilia to remove trapped particles.
SurfactantA substance that lowers surface tension in alveoli.
Counter-current flowFlow of two fluids in opposite directions, maintaining a gradient.
Concentration gradientThe difference in concentration between two regions.
Diffusion distanceThe distance a molecule must travel across an exchange surface.

Avoid these mistakes

1
Saying the alveolar wall is thick to prevent damage — it is one cell thick for short diffusion.
2
Saying ventilation is not needed because blood flow keeps the gradient — both ventilation and circulation are needed.
3
Saying the airways get shorter diffusion distances — the alveoli, not the airways, are the exchange surface.
4
Forgetting to use Fick's law terms (area, gradient, distance) in an efficiency explanation.

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