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2.5.10Structure and Functions in Living Organisms: Part 1

Bile — Edexcel International GCSE Science Double Award (Modular) - Biology Unit 1 Revision Notes & Topical Questions

5 min read 6 parts Lesson 23 of 32

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Section 1 of 6Making and storing bile

1Made in the liver
  • Made in the liver Liver cells continuously produce bile, a green, alkaline fluid.
    • Bile contains bile salts but no digestive enzymes.
2Stored in the gall bladder
  • Stored in the gall bladder Bile is carried along a duct to the gall bladder, where it is stored and slightly concentrated until needed.
3Released into the duodenum
  • Released into the duodenum When food leaves the stomach, bile flows along the bile duct into the first part of the small intestine and mixes with the food.

Section 2 of 6The two jobs of bile

Bile
1. Neutralises stomach acid
  • 1. Neutralises stomach acid Food arriving from the stomach is mixed with hydrochloric acid and is strongly acidic.
  • Bile is alkaline, so it neutralises the acid and makes the contents of the small intestine slightly alkaline.
  • This matters because enzymes in the small intestine have a higher optimum pH than stomach enzymes and would work badly in acid.
2. Emulsifies lipids
  • 2. Emulsifies lipids Bile salts break large drops of fat into many tiny droplets.
    • This is called emulsification.
  • The droplets have a much larger total surface area, so lipase enzymes can reach more of the fat at once.

Section 3 of 6What emulsification really is

A physical change
  • A physical change Emulsification is mechanical digestion.
    • Splitting a droplet into smaller droplets does not break chemical bonds or change the molecules.
  • A useful comparison is tearing a sheet of paper into small pieces: you have more pieces but the paper itself is unchanged.
Chemical digestion follows
  • Chemical digestion follows Once the surface area is increased, lipase breaks each lipid molecule into glycerol and three fatty acids, which are the chemical changes.
  • Bile therefore makes lipid digestion faster, but it does not carry out the chemical breakdown itself.
Exam wording
  • Exam wording Strictly it is the bile salts that emulsify fat, but saying 'bile emulsifies lipids' is accepted.

Section 4 of 6Putting it together in an answer

1
State that bile is made in the liver and stored in the gall bladder.
2
Say that it is released into the duodenum, where it neutralises acid from the stomach.
3
Explain that the alkaline conditions suit the enzymes of the small intestine.
4
Explain that bile salts emulsify lipids into small droplets with a larger surface area.
5
Conclude that lipase can then digest the lipids into fatty acids and glycerol faster.

Section 5 of 6Key terms

TermMeaning
BileAn alkaline fluid made in the liver that neutralises acid and emulsifies lipids.
Gall bladderA small organ that stores bile before it is released into the small intestine.
EmulsificationThe breaking of large lipid droplets into smaller ones, increasing surface area.
Bile saltsThe substances in bile that actually cause emulsification.
NeutraliseTo react with an acid so that the pH moves towards 7.

Section 6 of 6Exam technique

1
Saying bile is made in the gall bladder. It is made in the liver and only stored in the gall bladder.
2
Stating that bile digests fat chemically. It emulsifies fat; the lipase enzyme does the chemical digestion.
3
Describing emulsification as a chemical change. It is mechanical because no bonds are broken.
4
Forgetting to link the alkaline pH of bile to the higher optimum pH of enzymes in the small intestine.

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