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1.3.12Structure and Functions in Living Organisms: Part 2

The Role of Hormones: Basic — Edexcel International GCSE Science Double Award (Modular) - Biology Unit 2 Revision Notes & Topical Questions

5 min read 6 parts Lesson 24 of 24

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Part 1 of 5What a hormone is

Definition
  • Definition A hormone is a chemical substance made by a gland and carried in the blood to one or more target organs, where it alters their activity.
  • Hormones carry information from one part of the body to another and bring about a change.
Five to know
  • Five to know The hormones to learn are adrenaline, insulin, testosterone, progesterone and oestrogen.

Part 2 of 5Adrenaline: fight or flight

Adrenaline
Faster heart and breathing
  • Faster heart and breathing Delivers glucose and oxygen to muscle cells more quickly and removes carbon dioxide efficiently.
Blood redirected
  • Blood redirected More blood goes to muscles and less to non-essential organs such as the gut.
Wider vessels in muscle
  • Wider vessels in muscle Dilation of blood vessels in muscles lets more blood reach active tissues.
Glucose released
  • Glucose released Stored glycogen in the liver and muscles is broken down to glucose, which muscle cells use in respiration.

Part 3 of 5Insulin and blood glucose

1Blood glucose rises
  • Blood glucose rises After a meal the concentration of glucose in the blood goes above the normal range.
2Pancreas responds
  • Pancreas responds Cells in the pancreas detect the rise and secrete insulin into the blood.
3Glucose is taken up
  • Glucose is taken up Insulin makes muscles and the liver take glucose from the blood and store it as glycogen.
4Level returns to normal
  • Level returns to normal Once blood glucose is back in range, the pancreas stops releasing insulin.

Part 4 of 5Why glucose must be controlled

Too high
  • Too high Cells can lose water by osmosis, which is harmful.
Too low
  • Too low The brain may not receive enough glucose for respiration, which can lead to coma or even death.
Pancreas with two roles
  • Pancreas with two roles As an endocrine gland it secretes hormones into the blood, while separately it makes digestive enzymes that enter the gut.

Part 5 of 5Sex hormones and summary

HormoneSourceMain role
AdrenalineAdrenal glandsPrepares the body for fight or flight
InsulinPancreasLowers blood glucose by promoting uptake and storage as glycogen
TestosteroneTestesDevelopment of male reproductive organs and male secondary sexual characteristics
OestrogenOvariesFemale secondary sexual characteristics; repair of the uterus lining and control of ovulation
ProgesteroneOvariesMaintains the uterus lining in pregnancy and prevents further ovulation

Key terms

TermMeaning
HormoneA chemical messenger made by a gland and carried in the blood to target organs.
GlycogenA storage carbohydrate made of many glucose units, found in the liver and muscles.
Endocrine glandA gland that secretes hormones directly into the bloodstream.
Secondary sexual characteristicsFeatures that develop at puberty, such as voice change in males and breast development in females.
OvulationThe release of an egg cell from an ovary.

Avoid these mistakes

1
Saying insulin raises blood glucose; it lowers it by causing glucose to be stored as glycogen.
2
Forgetting that adrenaline acts on the heart, blood vessels and liver together to prepare muscles for action.
3
Mixing up the sources of the sex hormones: testosterone from the testes, oestrogen and progesterone from the ovaries.
4
Confusing glucose with glycogen in explanations of storage.

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