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2.2.1Reproduction and Inheritance

The Genome and Genes — Edexcel International GCSE Science Double Award (Modular) - Biology Unit 2 Revision Notes & Topical Questions

5 min read 6 parts Lesson 14 of 28

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Part 1 of 5From genome to protein

1Genome
  • Genome The genome is the complete set of DNA in an organism.
2Gene
  • Gene A gene is a short section of a DNA molecule.
3Amino acid sequence
  • Amino acid sequence Each gene carries a code that specifies a particular order of amino acids.
4Protein
  • Protein Chains of amino acids fold to make a protein, and the proteins made decide how a cell works and what the organism is like.

Part 2 of 5Proteins controlled by genes

Genes code for proteins
Structural proteins
  • Structural proteins Examples include collagen, which gives strength to skin and other tissues.
Enzymes
  • Enzymes Biological catalysts that control the rate of chemical reactions in the cell.
Hormones
  • Hormones Some hormones, such as insulin, are proteins and carry messages in the blood.

Part 3 of 5Chromosomes

Structure
  • Structure In the nucleus, each very long DNA double helix is coiled and supercoiled into a chromosome.
    • Chromosomes become visible under a microscope only when the cell is dividing.
Human number
  • Human number A normal human body cell has 23 pairs of chromosomes, which is 46 in total.
    • This is the diploid number, written 2n.
Pairs
  • Pairs One chromosome of each pair comes from the mother and the other from the father.
    • The two members of a pair are called a homologous pair.
Gene position
  • Gene position Each gene occupies a particular place on a chromosome, so the same gene is found at the same position on both chromosomes of a pair.

Part 4 of 5Chromosome numbers in species

OrganismChromosome pairsTotal in body cell
Human2346
Dog3978
Rice plant1224

Part 5 of 5Summary of the terms

TermLevel of organisation
GenomeAll the DNA of one organism
ChromosomeA structure of coiled DNA in the nucleus
GeneA short length of DNA that codes for one protein

Key terms

TermMeaning
GenomeThe entire DNA of an organism.
GeneA section of DNA that codes for a particular protein.
ChromosomeA coiled structure of DNA found in the nucleus.
DiploidHaving two sets of chromosomes, as in body cells (2n).
Homologous pairTwo chromosomes carrying the same genes, one from each parent.
Amino acidThe small molecules joined in a chain to make a protein.

Avoid these mistakes

1
Saying that a gene codes for a whole characteristic. A gene codes for a protein, and the protein influences the characteristic.
2
Confusing the number of pairs (23) with the total number of chromosomes (46).
3
Stating that all species have 46 chromosomes. The number differs between species.
4
Writing that chromosomes are always visible. They only appear as distinct structures during cell division.

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