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Structures and Functions in Living Organisms

Transport systems — Edexcel Linear - OL Revision Notes & Topical Questions

15 min read 19 parts Lesson 14 of 25 1 quiz

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Transpiration Practical, Blood Components and Immunity — EDEXCEL LINEAR - OL notes: Investigate transpiration with a potometer, describe the components of blood and explain how white blood cells and antibodies give immunity.A potometer measures water uptake, which is a good estim…

  • phagocytes
  • lymphocytes
  • memory cells
  • Worked example 1
  • Worked example 2
  • Worked example 3

Section 1 of 19Practical: investigating transpiration with a potometer

Potometer apparatus for measuring water uptake
Potometer apparatus for measuring water uptake

A potometer measures water uptake, which is a good estimate of the transpiration rate. There are two types: a simple one with a capillary tube and air bubble, and a reservoir type that lets the bubble be reset.

1
Cut a leafy shoot under water and fit it to the potometer, keeping the apparatus under water to avoid air bubbles.
2
Place a lamp 10 cm from the leaf and allow the plant to adapt to the new environment for 5–10 minutes.
3
Record the starting position of the air bubble (in mm).
4
Start a timer and leave for 30 minutes.
5
Record the final bubble position and calculate the distance moved, then the rate (mm per minute).
6
Repeat at other distances, or change another factor such as the temperature of the room (cold or warm).
Lamp distance (cm)Bubble distance (mm)Rate (mm/min)
10321.07

Using CORMS for light intensity: Change the intensity of the light; Observe/measure the distance moved by the bubble; Repeat; Measure the time; Same plant, temperature, humidity and air movement.

Section 2 of 19Components of blood

Components of blood and their proportions
Components of blood and their proportions

Blood consists of red blood cells, white blood cells, platelets and plasma. Over half the volume is plasma; most of the rest is red blood cells, with a small fraction of white cells and platelets.

ComponentStructureFunction
Red blood cellsBiconcave discs, no nucleus, contain haemoglobinCarry oxygen
White blood cellsLarge cells with a large nucleus; types differDefence against pathogens
PlateletsCell fragmentsBlood clotting
PlasmaClear, straw-coloured aqueous solutionTransports dissolved substances

Plasma transports

  • digested food and mineral ions (absorbed from the small intestine to cells);
    • carbon dioxide;
    • urea (a waste product carried to the kidneys);
    • hormones (from endocrine glands to target organs);
    • and heat energy from respiration, moved to cooler parts of the body or the skin where it can be lost.

Section 3 of 19White blood cells and immunity

A phagocyte engulfing and digesting a pathogen
A phagocyte engulfing and digesting a pathogen

White blood cells are part of the immune system and defend against pathogens.

Phagocytes
The two main types are phagocytes (which engulf and digest pathogens) and lymphocytes (which produce antibodies).
Antigen
An antigen is a marker on the surface of a cell or pathogen that the body sees as foreign and that triggers an immune response.
Lymphocytes provide a specific immune response because the antibodies they make fit only one type of antigen.
A pathogen with its antigens enters the body.
Lymphocytes with a matching receptor are activated and divide.
They produce antibodies specific to the antigen.
Antibodies bind the pathogen and mark it for destruction by phagocytes (or clump them together).
Memory cells
Some lymphocytes become memory cells that remain in the body for a long time.

An organism has immunity when its immune system can respond quickly if the pathogen re-enters, because antibodies are already present or memory cells can make antibodies rapidly. A person infected with a pathogen they are immune to does not suffer the disease or its symptoms.

Section 4 of 19Transpiration and the factors the potometer can test

Transpiration is the loss of water vapour from the leaves, mainly through the stomata.

1
It is faster when conditions increase evaporation and diffusion of water vapour out of the leaf.
2
In a potometer experiment you can test one factor at a time: light intensity (distance of the lamp), temperature (a warm or cold room), humidity (a plastic bag around the leaves) and air movement (a fan).
3
Higher light, higher temperature, lower humidity and more wind all raise the rate, so the bubble moves faster.
4
Because the water taken up is mostly lost, the rate of bubble movement is a good proxy for the rate of transpiration,
  • but it also includes a small amount of water used in photosynthesis and for support.

Section 5 of 19Worked examples

  1. A bubble moves 32 mm in 30 minutes. Calculate the rate in mm/min. [2]2 marks

  2. State what a potometer actually measures and why this estimates transpiration. [2]2 marks

  3. Name three substances transported by plasma. [3]3 marks

  4. Explain why antibodies are described as specific. [2]2 marks

  5. Explain why a second infection by the same pathogen causes no symptoms in an immune person. [3]3 marks

Section 6 of 19Vaccination

Vaccines help the body develop immunity to infectious diseases and have drastically reduced, or even eradicated, some diseases. A vaccine contains a harmless version of a pathogen (weakened or dead pathogens, or parts of them), and scientists make sure of this by killing or weakening the pathogen or using only its antigens.

1
The vaccine is injected; its antigens trigger the immune system.
2
Lymphocytes make antibodies (the primary response, which is slow and small).
3
Memory cells are produced and remain in the body for many years.
4
If the real pathogen later infects, memory cells make antibodies much sooner, faster and in greater quantity, before the pathogen can cause disease.

The individual is then immunethe response is so rapid that the pathogen cannot cause disease.

Section 7 of 19Platelets and blood clotting

Platelets are fragments of cells involved in clotting and forming scabs.

When the skin is broken, platelets arrive to stop the bleeding.
Fibrinogen
They release chemicals that cause soluble fibrinogen proteins in the plasma to convert into insoluble fibrin fibres,
  • which form a mesh across the wound trapping blood cells and forming a clot; this dries to a scab.
A clot prevents blood loss and stops pathogens entering.

Section 8 of 19Structure and function of the heart

The heart is a double pump.

Structure and function of the heart
Left
Oxygenated blood from the lungs enters the left side and is pumped to the body (systemic circuit); deoxygenated blood from the body enters the right side and is pumped to the lungs (pulmonary circuit).
The left ventricle has a thicker muscle wall than the right because it must pump blood at high pressure around the whole body,
  • whereas the right pumps only to the nearby lungs.
Structure and function of the heart
Vena cava
Deoxygenated blood from the body flows through the vena cava into the right atrium.
The atrium contracts, forcing blood through the tricuspid (atrioventricular) valve into the right ventricle.
Pulmonary artery
The ventricle contracts, pushing blood through the semilunar valve into the pulmonary artery to the lungs.
Oxygenated blood returns by the pulmonary vein to the left atrium, through the bicuspid valve to the left ventricle.
The left ventricle contracts and pushes blood through the semilunar valve into the aorta.

Remember arteries carry blood away from the heart. Both atria contract together and both ventricles contract together. A diagram is drawn as if the heart were in the chest, so the left side of the diagram is the person’s right.

Heart rate is the number of beats per minute (bpm). Exercise and adrenaline raise it. The resting rate is controlled by a group of cells in the right atrium called the pacemaker, which coordinates contraction and regulates the heart rate.

Section 9 of 19Coronary heart disease and its risk factors

The coronary arteries supply the cardiac muscle with oxygen and glucose. In coronary heart disease (CHD), layers of fatty material (plaque, mainly cholesterol) build up inside them, narrowing the lumen and reducing blood flow. Partial blockage causes severe chest pain (angina); complete blockage means cells cannot respire aerobically, leading to a heart attack.

Risk factorEffect
High blood pressureIncreases the force on artery walls and damages vessels
High-fat dietSpeeds up the build-up of fatty plaques
SmokingChemicals increase plaque build-up and blood pressure; carbon monoxide reduces the oxygen-carrying capacity of red blood cells
Genetics, stress, inactivityIncrease the likelihood of CHD

Section 10 of 19Putting it together: exam focus

Questions on this topic often ask you to follow blood from one place to another, so rehearse the route vena cava, right atrium, tricuspid valve, right ventricle, semilunar valve, pulmonary artery, lungs, pulmonary vein, left atrium, bicuspid valve, left ventricle, aorta. Heart valves ensure one-way flow; the muscle wall of the heart is cardiac muscle supplied by coronary arteries.

Section 11 of 19Worked examples

  1. Explain why the left ventricle wall is thicker than the right. [2]2 marks

  2. Explain how vaccination gives long-term immunity. [4]4 marks

  3. Describe the role of platelets in clotting. [3]3 marks

  4. State where the pacemaker is and what it does. [2]2 marks

  5. Explain how smoking increases the risk of CHD. [3]3 marks

Section 12 of 19Three types of blood vessel

The three main types of blood vessel are arteries, veins and capillaries. Smaller vessels that branch from arteries are arterioles (small arteries) and those that join into veins are venules (small veins). Each vessel is adapted to its function.

FeatureArteryCapillaryVein
Direction of bloodAway from the heartBetween arteries and veins, through tissuesTowards the heart
PressureHighFallingLow
WallThick, muscular and elasticOne cell thickThin, less muscle
LumenNarrowVery narrowWide
ValvesNoNoYes

Section 13 of 19Why each vessel is adapted as it is

Arteries carry blood at high pressure, so their walls are thick, muscular and elastic to withstand the pressure and recoil to push blood along. Veins carry blood at low pressure; a large lumen reduces resistance to flow and valves prevent the backflow of blood. Capillaries carry blood at low pressure within tissues and have walls one cell thick (a short diffusion distance), so substances easily diffuse in and out. Their walls are “leaky”, allowing blood plasma to leak out and form tissue fluid surrounding the cells.

Section 14 of 19General structure of the circulatory system

The circulatory system is a closed network of blood vessels connected to the heart, with blood flowing in one direction.

General structure of the circulatory system
Double circulation
It is a double circulation: the pulmonary circuit (heart to lungs and back) and the systemic circuit (heart to body and back),
  • so blood passes through the heart twice on each complete circuit.
Pulmonary artery
Arteries carry blood away from the heart to organs,
  • and this blood is usually oxygenated;
    • the pulmonary artery is the exception, carrying deoxygenated blood away from the heart.
Veins return blood to the heart, usually deoxygenated, and the pulmonary vein is the exception.
OrganVessel towards organVessel away from organ
HeartVena cava, pulmonary veinAorta, pulmonary artery
LungPulmonary arteryPulmonary vein
LiverHepatic artery, hepatic portal veinHepatic vein
KidneyRenal arteryRenal vein

Section 15 of 19Exchange at the capillaries and the role of tissue fluid

Blood pressure forces plasma through the thin capillary walls, forming tissue fluid that bathes the cells.

1
Oxygen, glucose and amino acids pass from the tissue fluid into the cells, while carbon dioxide and urea pass back.
2
Red blood cells and large proteins stay in the capillary.
3
Most tissue fluid returns to the capillaries and the remainder is collected by the lymph vessels and returned to the blood.
4
Because capillaries are so numerous and narrow, they bring blood within a few cells of every living cell in the body.

Section 16 of 19Pulse and pressure in different vessels

Blood leaves the heart in surges, so the pressure in arteries rises and falls with each beat; this surge can be felt as the pulse in an artery near the surface, for example at the wrist or neck.

Pulse and pressure in different vessels
By the time blood reaches the veins the pressure is low and steady,
  • so veins need valves and rely on contraction of surrounding skeletal muscles squeezing the veins to help push the blood towards the heart.
The total cross-section of all the capillaries is very large, so the blood slows down in them, giving more time for exchange.

In the exam, link each feature to a function: thick elastic wall to high pressure, thin wall to short diffusion distance, valves to preventing backflow, wide lumen to low resistance.

Section 17 of 19Worked examples

  1. Explain two ways in which the structure of a vein differs from that of an artery. [4]4 marks

  2. Explain why capillary walls are one cell thick. [2]2 marks

  3. Name the vessel taking blood from the heart to the lungs and say what type of blood it carries. [2]2 marks

  4. Why is the circulation described as a double circulation? [2]2 marks

  5. State the function of the valves in veins. [1]1 mark

Section 18 of 19Key terms

TermMeaning
PotometerApparatus that measures water uptake by a shoot.
PlasmaThe liquid part of blood.
AntigenA marker on a cell or pathogen that triggers an immune response.
AntibodyA protein made by lymphocytes that binds a specific antigen.
PhagocyteA white blood cell that engulfs and digests pathogens.
Memory cellA long-lived lymphocyte that gives a faster response on re-infection.
ImmunityThe ability to respond quickly to a pathogen and avoid disease.
TermMeaning
VaccineA harmless form of a pathogen that causes immunity without disease.
FibrinInsoluble protein fibres that form a blood clot.
PacemakerGroup of cells in the right atrium that controls heart rate.
Coronary arteryArtery supplying the heart muscle with oxygen and glucose.
AnginaSevere chest pain caused by partial blockage of coronary arteries.
PlaqueFatty deposit, mainly cholesterol, inside arteries.
TermMeaning
ArteryA vessel carrying blood away from the heart at high pressure.
VeinA vessel carrying blood back to the heart at low pressure.
CapillaryA tiny vessel with walls one cell thick where exchange occurs.
Tissue fluidPlasma that leaks out of capillaries and surrounds cells.
Double circulationA system in which blood passes through the heart twice per circuit.
ArterioleA small artery.

Section 19 of 19Exam technique

1
Saying red blood cells have a nucleus — they have none, to leave more room for haemoglobin.
2
Confusing antigens (on pathogens) with antibodies (made by lymphocytes).
3
Forgetting to allow the plant to adapt for 5–10 minutes in the potometer practical.
4
Saying memory cells make a new type of antibody — they remember one antigen.
1
Saying vaccines contain live dangerous pathogens — they are harmless forms.
2
Saying the left side of the heart carries deoxygenated blood.
3
Labelling the diagram without remembering it is drawn as if in the chest.
4
Saying a blockage makes cells respire anaerobically — they lack oxygen and the muscle is damaged.
1
Saying all arteries carry oxygenated blood — the pulmonary artery does not.
2
Saying veins have thick muscular walls.
3
Forgetting that capillaries have no valves.
4
Saying veins carry blood away from the heart.

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