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2cStructures and Functions in Living Organisms

Biological molecules — Edexcel Linear - OL Revision Notes & Topical Questions

5 min read 7 parts Lesson 3 of 25 1 quiz

📚 Edexcel Linear - OL Hub / Topical Revision
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Curriculum Equation Key قوانين الرقم الهيدروجيني والاتزان الأيوني - pH & Acid-Base Equilibrium FormulasFast Exam Solution
pH = -log[H⁺] | pOH = -log[OH⁻] | pH + pOH = 14 | [H⁺][OH⁻] = 10⁻¹⁴
Word Equation & Conditions: الرقم الهيدروجيني = -لوغاريتم تركيز أيون الهيدروجين | pH + pOH = 14
Location & Specifications: الاتزان الأيوني، كيمياء 3 ثانوي، التحصيلي، و AP Chemistry.
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Lesson summary

Biological molecules Edexcel O Level Linear Biology notes: identify the chemical elements present in carbohydrates, proteins and lipids (fats and oils)Haemoglobin is a globular protein with 4 chains and haem groups (quaternary).Collagen is fibrous3 chains in a triple helix, stron…

  • Biological molecules Edexcel O Level Linear Biology: what to do next
  • Condensation
  • Hydrolysis
  • Glycosidic bond
  • Ester bond
  • Peptide bond

Part 1 of 6Key ideas

Haemoglobin is a globular protein with 4 chains and haem groups (quaternary).
Collagen is fibrous
3 chains in a triple helix, strong and insoluble.
Water has high specific heat capacity and high latent heat of vaporisation.
Sucrose = glucose + fructose; lactose = glucose + galactose.

Part 2 of 6Syllabus points

1
identify the chemical elements present in carbohydrates, proteins and lipids (fats and oils)
2
describe the structure of carbohydrates, proteins and lipids as large molecules made up from smaller basic units
  • starch and glycogen from simple sugars
  • protein from amino acids
  • and lipid from fatty acids and glycerol
3
practical: investigate food samples for the presence of glucose, starch, protein and fat
4
understand the role of enzymes as biological catalysts in metabolic reactions
5
understand how temperature changes can affect enzyme function, including changes to the shape of active site
6
practical: investigate how enzyme activity can be affected by changes in temperature
7
understand how enzyme function can be affected by changes in pH altering the active site

Part 3 of 6Process & sequence

1
Primary: amino acid sequence
2
Secondary: α-helix / β-sheet (H-bonds)
3
Tertiary: 3D folding (ionic, disulfide, H, hydrophobic)
4
Quaternary: several chains
1
Heat sample with Benedict’s – no colour change: no reducing sugar.
2
Boil a new sample with dilute HCl (hydrolysis).
3
Neutralise with sodium hydrogencarbonate.
4
Heat with Benedict’s again.
5
Brick-red now → non-reducing sugar present.

Part 4 of 6Summary

Summary
Monomers join by condensation; polymers break by hydrolysis.
Cellulose is made of β-glucose.
Biuret reagent turns purple with protein.

Part 5 of 6Keep going

Biological molecules Edexcel O Level Linear Biology: what to do next

These Biological molecules Edexcel O Level Linear Biology notes covered the key ideas, worked examples and exam technique for this topic. Check your Biological molecules Edexcel O Level Linear Biology understanding with the practice questions below, then reread any Biological molecules Edexcel O Level Linear Biology point you were unsure about before moving on.

Biological molecules Edexcel O Level Linear Biology revision notes

Part 6 of 6Compare: Compare

Biological molecules compared
MoleculeMonomerBondStructureFunctionTest
Starch (amylose)α-glucoseα-1,4 glycosidicUnbranched helixEnergy store in plants – compactIodine → blue-black
Amylopectin / glycogenα-glucoseα-1,4 and α-1,6Branched (glycogen more)Rapid glucose releaseIodine
Celluloseβ-glucoseβ-1,4 glycosidicStraight chains, H-bonds → microfibrilsCell wall strength—
TriglycerideGlycerol + 3 fatty acidsEsterHydrophobicEnergy store, insulationEmulsion test
PhospholipidGlycerol + 2 fatty acids + phosphateEsterHydrophilic head, hydrophobic tailsMembrane bilayer—
ProteinAmino acidsPeptidePrimary → quaternaryEnzymes, haemoglobin, collagenBiuret → purple
Water—Hydrogen bondsPolar moleculeSolvent, coolant, high SHC—

Key terms

Command terms

Command terms
Give / State / Name
Recall a fact; one idea per mark.
Define
Give the exact meaning using the specification keywords.
Describe
Give an account of what happens / the pattern in data, quoting values; no reasons needed.
Explain
Give reasons with linked statements (cause → effect). Each linked step is usually a separate marking point.
Suggest
Use knowledge in a new context; more than one answer may be accepted.
Compare
Similarities and differences; each point must refer to both items.
Calculate
Show working; include units; check significant figures. Method marks are given even if the final answer is wrong.
Discuss
Explore the issue from different angles and link the points.
Evaluate / Assess
Weigh strengths and weaknesses and reach a supported judgement.
Deduce
Draw a conclusion from the information given.
Justify
Support a statement/choice with evidence.

Exam technique

Keywords the mark scheme looks for in this lesson

Keywords the mark scheme looks for in this lesson
Monomer · Condensation · Hydrolysis · Glycosidic bond · Ester bond · Peptide bond · Reducing sugar · Hydrogen bond
Learn each definition in the Key words tab exactly; a missing keyword in a definition usually loses the mark.

How to get full marks (examiner guidance)

How to get full marks (examiner guidance)
Use specification keywords exactly (e.g. eukaryotic/prokaryotic, enzyme–substrate complex, active site, complementary).
Link ideas
Link ideas for “explain” each marking point is usually a cause → consequence step; unlinked facts often score nothing.
Use the information in the question
“discuss/evaluate” answers must use the data provided and match the number of marks.
Convert units carefully (mg → g, cm³ → dm³) and show working for calculations.
Avoid vague words
“it”, “stuff”, “things”, “goes up”, “energy is made”. Name the substance and the process.
Do not extrapolate a graph line beyond the data or to zero unless asked.
Six-mark extended responses are marked on content AND a logical, linked line of reasoning.

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