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2.2Structures and Functions in Living Organisms

Cell Structure — Edexcel Linear - OL Revision Notes & Topical Questions

10 min read 12 parts Lesson 17 of 25 1 quiz

📚 Edexcel Linear - OL Hub / Topical Revision
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Lesson summary

Cell Structure, Plant and Animal Cells and Specialised Cells — EDEXCEL LINEAR - OL notes: Describe the functions of cell structures, compare plant and animal cells, and explain how cells differentiate and are adapted to their functions.Cells are surrounded by a cell membrane, whi…

  • organelles
  • Cell differentiation
  • Worked example 1
  • Worked example 2
  • Worked example 3
  • Worked example 4

Section 1 of 12Structures in cells and their functions

Cells are surrounded by a cell membrane, which separates them from the external environment.

Structures in cells and their functions
Inside it is the cytoplasm, a jelly-like substance of water with dissolved substances.
Organelles
Eukaryotic cells have organelles within the cytoplasm.
Some structures, like ribosomes and mitochondria, are too small to be seen with a light microscope but can be seen with an electron microscope.
Mitochondrion refers to one organelle and mitochondria to more than one (muscle cells contain many mitochondria).
StructureFunction
NucleusContains genetic material (chromosomes)
CytoplasmSite of many chemical reactions; contains water and solutes
Cell membraneControls substances entering and leaving the cell
Cell wall (plants)Cellulose; gives extra support and shape, prevents bursting
MitochondriaSite of aerobic respiration
ChloroplastsSite of photosynthesis; contain chlorophyll
RibosomesSite of protein synthesis
Permanent vacuoleContains cell sap; supports plant cells keeping them firm (turgid)

Section 2 of 12Animal and plant cells compared

StructureAnimal cellPlant cell
Nucleus, cytoplasm, cell membraneYesYes
Mitochondria, ribosomesYesYes
Cell wallNoYes (cellulose)
ChloroplastsNoYes (in leaves and stems)
VacuoleSmall and temporaryLarge and permanent

A plant cell showing chloroplasts would be found in the leaves of a plant.

Section 3 of 12Cell differentiation and specialised cells

Cell differentiation is the process by which a cell changes to become specialised, developing the structure and subcellular structures it needs for its function.

1
Genes in the nucleus control this.
2
For example, to form a nerve cell the cytoplasm and cell membrane elongate to form connections over long distances.
3
As an organism develops, cells differentiate into different types.
4
Most animal cells differentiate early; adult stem cells keep the ability to replace and repair cells like blood and skin cells.
5
In plants, many cells retain the ability to differentiate throughout life.
Specialised cellAdaptationFunction
Ciliated cellHair-like cilia that beatMove mucus and trapped particles in the trachea and bronchi towards the throat
Nerve cellLong, with extensionsConduct impulses over long distances
Red blood cellBiconcave shape, no nucleus, packed with haemoglobinTransport oxygen efficiently
Root hair cellLong extension, thin wallAbsorb water and minerals with a large surface area
Palisade mesophyll cellColumn-shaped, many chloroplasts, packed beneath the upper epidermisPhotosynthesis

Section 4 of 12Using the microscope and reading cell diagrams

A light microscope shows the nucleus, cytoplasm, cell membrane, cell wall, chloroplasts and the vacuole, but not ribosomes or the detailed structure of mitochondria, which need an electron microscope with much higher magnification and resolution.

Using the microscope and reading cell diagrams
When you draw a cell, use a sharp pencil, draw clear continuous lines, label with ruled lines and do not shade.
Magnification = size of the image ÷ size of the real object; for example, an image of 40 mm for a cell of 0.02 mm gives a magnification of ×2000.
  • Cell size in plants is usually larger than in animal cells, and the regular shape of plant cells is due to the cell wall.

When comparing cells, always give a similarity before a difference, for example: both animal and plant cells have a nucleus, but only plant cells have a cell wall. Always link an adaptation to its function, such as many mitochondria in a sperm tail for energy.

Section 5 of 12Worked examples

  1. State the function of the mitochondria. [1]1 mark

  2. Give three structures found in plant cells but not in animal cells. [3]3 marks

  3. Explain how a red blood cell is adapted to carry oxygen. [3]3 marks

  4. Define differentiation. [1]1 mark

  5. Explain why palisade cells contain many chloroplasts. [2]2 marks

Section 6 of 12What are stem cells?

A stem cell is an undifferentiated cell of an organism that can divide by mitosis an unlimited number of times.

What are stem cells?
When a stem cell divides, the cells formed may remain undifferentiated (and can divide again to form more stem cells) or may differentiate into specialised cells.
Undifferentiated cells have not specialised into a particular cell type to carry out a particular function.
Embryonic stem cellsAdult stem cells
SourceEmbryosSome tissues and organs in animals, e.g. bone marrow
PotentialCan differentiate into all the different cell typesCan differentiate into a limited number of cell types

Section 7 of 12Stem cell therapy

Stem cells can be used to treat illnesses where cells in the body are not functioning properly and need replacing or repairing: stem cell therapy.

Stem cell therapy
An advantage of embryonic stem cells is that they can make any cell type, whereas adult stem cells make fewer.
The problem is ethical: some people see human embryos as potential human lives and many object to destroying embryos to obtain the cells.

Example human blood cells are produced from adult stem cells in the bone marrow, which can differentiate only into blood cells: red blood cells, white blood cells and platelet-forming cells.

Stem cell therapy
Red blood cells can treat anaemia, in which blood cannot transport enough oxygen.
White blood cells (phagocytes and lymphocytes) can improve immunity in patients with a reduced immune system.
Platelets can treat patients with clotting problems.

Stem cells from a healthy donor’s bone marrow can be transplanted into a patient’s bone marrow.

Antigens
A disadvantage is that donor cells carry different antigens (cell surface proteins) from the patient’s cells,
  • so the patient must take immunosuppressant drugs to prevent rejection.
It is far better to use the patient’s own stem cells if possible: the cells will have the same genes and antigens,
  • so no rejection occurs and no immunosuppressants are needed.

Section 8 of 12Evaluating the use of stem cells

BenefitsRisks and concerns
Can replace damaged cells and treat diseases that are otherwise hard to treatEmbryonic cells need embryos, which raises ethical objections
Embryonic stem cells can form any cell typeDonor cells may be rejected unless immunosuppressants are used
Patient’s own cells avoid rejectionRisk of infection or of uncontrolled division (tumours)
Adult stem cells avoid destroying embryosAdult stem cells form only limited types of cell; treatments can be expensive

You do not need to recall specific diseases that can be treated with stem cells, but you do need to describe what a stem cell is, the differences between embryonic and adult stem cells, and the advantages and disadvantages of their use. The main issue with embryonic stem cells is that they can only be sourced from embryos, which many people consider unethical.

Section 9 of 12Stem cells in context

Stem cells in a developing embryo form all the specialised cells of the body.

1
In adults they are kept in reserve in places such as bone marrow, where they divide to replace red blood cells, white blood cells and platelets.
2
Because their potential is limited, adult stem cells are less versatile.
3
Research into using stem cells to treat damage, such as spinal injury or diabetes, is continuing, but treatments are not yet routine.
4
Society debates how much of this research should be permitted, how embryos should be treated and who should pay.
5
When you evaluate, state a benefit, a risk or concern, and make a judgement based on both.

Section 10 of 12Worked examples

  1. Define a stem cell. [2]2 marks

  2. Give one difference between embryonic and adult stem cells. [1]1 mark

  3. Explain why a patient receiving donor bone marrow stem cells needs immunosuppressant drugs. [2]2 marks

  4. Give one ethical objection to using embryonic stem cells. [1]1 mark

  5. Describe one use of stem cells from bone marrow. [2]2 marks

Section 11 of 12Key terms

TermMeaning
OrganelleA structure inside a cell with a specific function.
MitochondrionOrganelle where aerobic respiration takes place.
ChloroplastOrganelle where photosynthesis takes place.
DifferentiationThe process of a cell becoming specialised.
Specialised cellA cell with adaptations for a particular function.
TurgidFirm because the vacuole is full of water.
TermMeaning
Stem cellAn undifferentiated cell that can divide by mitosis and differentiate.
Embryonic stem cellA stem cell from an embryo that can become any cell type.
Adult stem cellA stem cell in some adult tissues that can form a limited number of cell types.
Stem cell therapyUsing stem cells to replace or repair faulty cells.
AntigenA protein on the cell surface that the immune system can recognise.
ImmunosuppressantA drug that reduces the immune response to prevent rejection.

Section 12 of 12Exam technique

1
Saying mitochondria produce energy — they release energy from respiration.
2
Saying plant cells have no mitochondria.
3
Saying all plant cells contain chloroplasts — root cells do not.
4
Confusing the cell wall (support) with the cell membrane (controls what passes).
1
Saying adult stem cells can become any type of cell.
2
Saying stem cells divide by meiosis — it is mitosis.
3
Forgetting that the patient’s own cells avoid rejection.
4
Giving only the benefits when asked to evaluate.

Last updated:

Cambridge 9700 AS Biology Core Formula

Magnification Triangle & Unit Conversion

Formula: M = I / A  ⇔  A = I / M  ⇔  I = M × A

Units: 1 mm = 1,000 μm = 1,000,000 nm.
Rule: Convert Image size (ruler mm) to μm by ×1,000 before dividing by Actual size.

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