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BIOLOGY · Stage 7 · Chapter 2: Cells and Organisation

Biology 2.2 The cell story — Microscopes and Cell Theory — Alhussan International Academy - Biology (Stages 7-9) Revision Notes & Topical Questions

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2.2 The cell story — Microscopes and Cell Theory — Alhussan International Academy — Biology (Stages 7–9) notes: Describe how improvements in microscopes led to the discovery of cells and the development of cell theory.Cell size — cells are far too small to see, so nobody knew bef…

  • Invention of the microscope
  • New technology
  • Hooke's cells
  • Van Leeuwenhoek
  • Scientific theory
  • Spontaneous generation

Section 1 of 6Why cells were discovered late

  • Cell size
    • cells are far too small to see, so nobody knew before the 1600s that living things are made of cells.
  • Invention of the microscope
    • the first cells were seen in Europe in the 17th century, about 350 years ago.
    • Early microscopes used polished glass lenses, and they were tiny and did not look like modern ones.
    • Better lens making allowed scientists to see more detail.
  • New technology
    • the story of the cell shows how new technology leads to new knowledge.

Section 2 of 6Early microscopists

DateScientistDiscovery
1665Robert HookeLooked at a thin slice of cork with a simple microscope, saw a honeycomb structure and called each unit a cell
1670–1683Anton van LeeuwenhoekMade fine polished lenses, looked at pond water and was the first person to see living cells
1833Robert BrownSaw the internal structure of plant cells and discovered the nucleus, which contains the genetic material
  • Hooke's cells
    • he saw only the walls of dead cork cells, and he made careful drawings.
  • Van Leeuwenhoek
    • he was not a trained scientist, and he made detailed drawings of the tiny living organisms he saw.

Section 3 of 6Development of the cell theory

DateScientistDiscovery
1838Matthias Jakob SchleidenSuggested that all plant tissues are made of cells, which are the building blocks of plants
1839Theodor SchwannStated that the cell is the basic unit of structure of all organisms and that all organisms consist of one or more cells
1845Carl-Heinrich BraunSimplified the wording: cells are the basic unit of life
1855Rudolf VirchowProposed that new cells come from existing cells
  • Credit
    • Schwann is given the credit for the modern cell theory.

Section 4 of 6Statements of the cell theory

  1. All living organisms are made of one or more cells.
  2. The cell is the basic unit of structure and function in living things.
  3. All cells arise from pre-existing cells by cell division.
  • Scientific theory
    • a well-tested explanation supported by a lot of evidence, not just a guess.
    • It can be changed if new evidence is found.
  • Spontaneous generation
    • the older idea that living things could appear from non-living material such as rotting meat, which the third statement replaced.

Section 5 of 6Why the cell theory was accepted in the 19th century

  • Doubt earlier
    • many people did not believe Hooke and van Leeuwenhoek because good microscopes were hard to make.
    • Without a microscope nobody could see the cells and microorganisms that were described.
  • Better microscopes
    • more people had good microscopes in the 19th century.
  • Communication
    • easier communication between countries let scientists compare findings and agree on what they saw.
  • Cumulative science
    • scientific knowledge is built by many people over time, each using and testing the work of others.

Section 6 of 6From light to electron microscopes

  • Light microscope
    • magnifies up to about 1000 times and shows the nucleus, cytoplasm and chloroplasts.
  • Electron microscope
    • developed in the 1930s, it uses beams of electrons and magnifies up to 1 million times.
    • It reveals ribosomes, the detail of mitochondria and the cell membrane.
  • Cell membrane
    • it is too thin to see with a light microscope.
    • Its existence was shown first by experiments on how substances enter cells and later confirmed with the electron microscope.

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