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BIOLOGY · Stage 7 · Chapter 2: Cells and Organisation

Biology 2.7 Modelling cells — Scientific Models in Cell Biology — Alhussan International Academy - Biology (Stages 7-9) Revision Notes & Topical Questions

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2.7 Modelling cells — Scientific Models in Cell Biology — Alhussan International Academy — Biology (Stages 7–9) notes: Explain why scientists use models to study cells and describe the strengths and limitations of a model.Model = a simplified representation of something that help…

  • When models are used
  • Good model
  • Physical models
  • Computer models
  • Membrane model
  • Clay animal cell

Section 1 of 6What is a scientific model

  • Model = a simplified representation of something that helps to explain it, make predictions or communicate an idea.
  • When models are used
    • when the real thing is too small, too large, too slow, too fast or too complicated to study directly.
  • Cells
    • they are too small to see in detail with the unaided eye, so biologists use many kinds of model.
  • Good model
    • it helps to remember the structure of a system and may show how it works.
  • Bad model
    • it confuses and can give misconceptions about a biological system.

Section 2 of 6Types of model for cells

  • Physical models
    • 3-D structures made from modelling clay, boxes, plastic bags or sweets, with different materials representing organelles.
  • Analogies
    • comparing a cell to something familiar such as a factory or a city.
    • The nucleus is like the control office, mitochondria like power stations and the membrane like a security gate.
  • Diagrams
    • labelled drawings that show how parts are related.
  • Computer models
    • animations and simulations that show how organelles move or how substances cross a membrane.
  • Membrane model
    • a bag with small holes shows that small particles pass through while large ones are stopped.

Section 3 of 6Building a model cell

  1. Decide what each part of the model will represent and write a key.
  2. Choose sensible materials,
    • such as a clear plastic bag for the membrane, gel for cytoplasm, a ball or grape for the nucleus and beads for mitochondria.
  3. Build the animal cell and the plant cell, giving the same structures the same colour in both so similarities are clear.
  4. Label each material and what it represents, and add a scale to show the size difference between animal and plant cells.
  5. Take care over relative sizes, because ribosomes are many times smaller than mitochondria.

Section 4 of 6Examples of student models

  • Clay animal cell
    • modelling clay lets the cell be an irregular shape, as animal cells are.
    • Only the structures the student could remember were labelled.
  • Plant cell in a green box
    • dried peas in a balloon stand for chloroplasts and a grape stands for the nucleus.
    • The balloon represents the membrane and cytoplasm, and the box represents the cell wall.
    • The full balloon pushes outwards on the box like the vacuole pushes on the wall to keep a plant cell firm.
  • Limitations of the box model
    • a box is rigid and flat sided, but a real cell wall is made of a mesh of fibres.

Section 5 of 6Evaluating a model

StrengthsLimitations
Makes a tiny structure big enough to see and handleMay show the wrong size, shape or proportions
Shows how parts fit togetherIs often fixed, but real cells move and change
Helps to explain and remember functionsMaterials do not behave like living parts
Can be used to make predictionsPredictions must still be tested by experiment
  • Factory analogy
    • it shows each organelle has a job but not that cells are alive, grow and reproduce.

Section 6 of 6Models change with evidence

  • Scientific models
    • they are changed when new evidence is found.
  • Early cell models
    • they showed only a blob with a nucleus.
  • Electron microscope images
    • they added mitochondria, ribosomes and membranes to the model.
  • Membrane model
    • the fluid mosaic model describes proteins floating in a double layer of lipids, and it was improved as new techniques revealed more.

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