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BIOLOGY · Stage 9 · Chapter 11: Human Genetics and Development

Biology 11.3 Boy or girl? Sex inheritance in humans — X and Y Chromosomes — Alhussan International Academy - Biology (Stages 7-9) Revision Notes & Topical Questions

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11.3 Boy or girl? Sex inheritance in humans — X and Y Chromosomes — Alhussan International Academy — Biology (Stages 7–9) notes: Explain how sex is determined by the X and Y chromosomes and use a Punnett square to show the probability of having a boy or girl.Inheritance — at fert…

  • Gene copies
  • Gene number
  • Sex chromosomes
  • Deciding the sex
  • Independence
  • Sex-linked characteristics

Section 1 of 5Chromosomes from each parent

  • Inheritance
    • at fertilisation the embryo gets half of its chromosomes from the egg (its mother) and half from the sperm (its father).
    • Each gamete contains 23 chromosomes and each cell of the embryo contains 46.
  • Gene copies
    • chromosomes come in pairs that carry the same genes, so you get one copy of each gene from your mother and one from your father.
  • Gene number
    • each of the 46 chromosomes carries around 1000 genes.

Section 2 of 5Chromosomes and sex

  • Autosomes
    • 22 of the 23 pairs have two chromosomes of the same size and shape with matching genes, in both males and females.
  • Sex chromosomes
    • the 23rd pair determines whether a person is female or male.
    • The X chromosome is relatively large.
    • The Y chromosome is much smaller with just a few genes.
  • Females
    • they have two X chromosomes (XX).
  • Males
    • they have one X and one Y chromosome (XY).
    • The SRY gene on the Y chromosome makes the embryo develop testes.

Section 3 of 5Gametes carry one of each pair

  • Meiosis
    • gametes are made by meiosis, which halves the chromosome number, so each gamete has one chromosome from each pair.
  • Eggs
    • women's cells are XX, so every egg contains an X chromosome.
  • Sperm
    • men's cells are XY, so half the sperm carry an X chromosome and half carry a Y chromosome.
  • Deciding the sex
    • the sex of the baby depends on which sperm fertilises the egg.
    • All sperm have an equal chance, so it is a matter of chance.
    • An X sperm gives XX, a girl; a Y sperm gives XY, a boy.

Section 4 of 5Punnett square for sex

X (mother)X (mother)
X (father)XX girlXX girl
Y (father)XY boyXY boy
  • Probability
    • each child has a 1 in 2 (50%) chance of being a girl and 1 in 2 (50%) of being a boy.
  • Independence
    • every pregnancy has the same chances, so having three boys does not make a girl more likely next time.
  • Ratio
    • the ratio of boys to girls in a population is about 1:1, though a small sample may differ by chance.

Section 5 of 5Other points

  • The father's sperm decides the sex, because the mother can only give an X.
  • Sex-linked characteristics
    • some characteristics, such as red-green colour blindness, are controlled by genes on the X chromosome.
    • Males have only one X, so a single faulty allele shows up.
    • Females must inherit the faulty allele on both X chromosomes, so more males than females are colour blind.

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