BIOLOGY · Stage 9 · Chapter 11: Human Genetics and Development
Biology 11.2 Fertilisation: new life begins — Nuclei Fusion and Zygote Formation — Alhussan International Academy - Biology (Stages 7-9) Revision Notes & Topical Questions
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11.2 Fertilisation: new life begins — Nuclei Fusion and Zygote Formation — Alhussan International Academy — Biology (Stages 7–9) notes: Describe how fertilisation occurs, how the zygote becomes an embryo that implants in the uterus, and how twins and IVF arise.Fertilisation = the…
- Sperm cells
- Cell division
- Implantation
- Development
- Identical twins
- IVF (in vitro fertilisation)
Section 1 of 5What fertilisation is
- Fertilisation = the fusion of the nucleus of a sperm with the nucleus of an egg to form a single cell called a zygote.
- Each nucleus has 23 chromosomes, so the zygote has the normal 46, with half from each parent.
- The zygote has a new combination of DNA, so the offspring differs genetically from either parent.
- Egg cells
- they are large, contain a food store, cannot move themselves and are formed and stored in the ovaries before birth.
- A few mature and one is released each month once a girl is a teenager.
- Sperm cells
- they are very small and made in the testes, and boys make millions every day once they are teenagers.
Section 2 of 5Stages of fertilisation
- During intercourse, semen is released into the vagina near the cervix.
- Millions of sperm swim through the cervix and uterus into the oviducts using their tails, and many die on the way.
- If an egg has been released recently, sperm surround it and enzymes in the acrosomes digest a path through the jelly coat.
- One sperm head enters the egg and the egg forms a protective layer at once, so no other sperm can enter.
- The sperm nucleus fuses with the egg nucleus, forming the zygote.
- Timing
- an egg survives about 24 hours after ovulation and sperm live inside the female body for several days,
- so intercourse around ovulation gives the highest chance of pregnancy.
Section 3 of 5From zygote to embryo
- Cell division
- the zygote divides by mitosis as it travels down the oviduct to the uterus, taking about 3 to 4 days.
- First two cells form, then four, then eight, until a ball of cells forms.
- Embryo
- the ball of cells is called the embryo.
- Implantation
- about 6 to 7 days after fertilisation the embryo sinks into the soft lining of the uterus.
- Development
- the cells keep dividing and begin to specialise into tissues and organs.
- Fetus
- from about eight weeks, when the main organs have formed, the developing baby is called a fetus.
Section 4 of 5The importance of genes
- Control
- once the embryo begins to grow, the inherited genes determine its characteristics.
- They control skin and eye colour, how the heart forms and the length of the arms and legs.
- Sex
- the chromosomes also determine whether the individual is a boy or a girl.
Section 5 of 5Twins and fertility treatment
1Identical twins2 points
- they form when the embryo splits in two early on.
- They have the same genes and are always the same sex.
2Non-identical twins2 points
- they form when two eggs are fertilised by two sperm.
- They are as different as other brothers and sisters.
3IVF (in vitro fertilisation)3 points
- eggs are collected from the mother and fertilised with sperm in a laboratory dish.
- A few embryos are then placed in the uterus.
- It helps couples who cannot conceive naturally.
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