15.1Drugs
Drugs — Cambridge IGCSE Biology 0610 Revision Notes & Topical Questions
5 min read 10 parts Lesson 2 of 3 1 quiz
Lesson summary
15.1 Drugs — IGCSE BIOLOGY notes: Define a drug and describe the use of antibiotics, why they do not affect viruses, and how resistant bacteria such as MRSA arise and are limited.Drug = any substance taken into the body that modifies or affects chemical reactions in the body.Medi…
- Medicinal drug
- Stopping early
- Rapid reproduction
- Resistant infections
- Percentage killed
- Antibiotic resistance
Part 1 of 8Drugs
Drug
Drug any substance taken into the body that modifies or affects chemical reactions in the body.
Medicinal drug
- Medicinal drug a drug used to treat or prevent disease or relieve symptoms, such as antibiotics and painkillers.
Part 2 of 8Antibiotics
Antibiotics
- Antibiotics used to treat bacterial infections.
- They kill bacteria or stop their growth.
- They act on structures and processes found only in bacterial cells, not human cells.
Viruses
- Viruses antibiotics do not affect them.
- Viruses have no cell wall or metabolism of their own and reproduce inside host cells.
- There is no bacterial structure for the antibiotic to attack.
Part 3 of 8Bacteria and viruses compared
| Feature | Bacteria | Viruses |
|---|---|---|
| Cellular | Yes: cell wall, ribosomes, own metabolism | No: use host cell machinery |
| Antibiotic targets present | Yes | No |
| Treated with antibiotics | Yes | No |
Part 4 of 8Development of antibiotic resistance
1
A population of bacteria varies, and a random mutation makes one bacterium resistant.
2
The antibiotic is used and susceptible bacteria are killed.
3
The resistant bacterium survives because it is better adapted.
4
It reproduces rapidly by binary fission and passes on the resistance allele.
5
The resistant strain becomes more common.
6
The antibiotic no longer works against this strain, for example MRSA.
Part 5 of 8Why overuse increases resistance
Overuse
- Overuse for viral infections or in livestock increases the chance that resistant strains are selected.
Stopping early
- Stopping early a course stopped early may leave the more resistant bacteria alive to multiply.
Rapid reproduction
- Rapid reproduction bacteria reproduce so fast that resistance spreads quickly through a population.
Resistant infections
- Resistant infections are harder to treat and may need different or stronger antibiotics.
Part 6 of 8Minimising resistance
Minimising resistance
Use antibiotics only when essential.
Complete the full course so all bacteria, including less susceptible ones, are killed.
Part 7 of 8Percentage of bacteria killed
- Percentage killed (initial number − final number) ÷ initial number × 100.
Part 8 of 8More from the specification
- Incidence
- Number of new cases in a period per population.
Key terms
| Term | Meaning |
|---|---|
| Drug | A substance that modifies or affects chemical reactions in the body. |
| Antibiotic | A drug that kills bacteria or stops their growth and does not affect viruses. |
| Antibiotic resistance | The ability of bacteria to survive an antibiotic, arising by mutation and spreading by natural selection. |
| MRSA | Methicillin-resistant Staphylococcus aureus, a bacterium resistant to many antibiotics. |
| Mutation | A random change in genetic material. |
| Pathogen | A disease-causing organism. |
Avoid these mistakes
1
Saying antibiotics treat colds and flu — these are viral infections.
2
Saying antibiotics cause resistance mutations — the mutations are random and the antibiotic selects them.
3
Saying people become resistant — the bacteria do.
4
Stopping the course when feeling better — the full course must be finished.
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