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BIOLOGY · Stage 7 · Chapter 3: Microorganisms and Decomposers

Biology 3.4 Using science to prevent disease — Hygiene, Antibiotics and Vaccines

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3.4 Using science to prevent disease — Hygiene, Antibiotics and Vaccines — Alhussan International Academy — Biology (Stages 7–9) notes: Explain how infections spread and how hygiene, antibiotics and vaccination prevent or treat infectious disease.Droplet infection — breathing, ta…

  • Direct contact
  • Contaminated food and drink
  • Break in the skin
  • Scientific advice
  • Evidence for masks
  • Evidence for social distancing

Section 1 of 7How microorganisms spread

1Droplet infection4 points
  • breathing, talking, coughing or sneezing forces tiny droplets containing microorganisms out of the mouth and nose.
  • Other people breathe in the droplets.
  • A sneeze sends droplets out at about 160 km/h.
  • Examples are influenza and TB.
2Direct contact2 points
  • spread by the skin of an infected person or by objects covered in microorganisms.
  • Examples are verrucas, or microorganisms getting in through the mouth.
3Contaminated food and drink2 points
  • water contaminated by human waste, or raw or under-cooked food, takes microorganisms straight into the body.
  • Examples are diarrhoea and cholera.
4Break in the skin2 points
  • cuts, animal scratches and needle punctures let microorganisms straight into the blood.
  • An example is tetanus.

Section 2 of 7Applying science to COVID-19

  • COVID-19
    • a new disease caused by a virus that spreads by droplet infection and by direct contact.
  • Scientific advice
    • Wash hands often with soap and use antiseptic hand gel.
    • Wear a face mask over the mouth and nose.
    • Meet as few people as possible, avoid crowded places and keep a distance, meeting outdoors if possible.
    • Cough or sneeze into a tissue or the elbow.
    • Stay at home, away from other people, when ill.
  • Evidence for masks
    • graphs showed that countries with mask-wearing policies had fewer deaths from COVID-19.
  • Evidence for social distancing
    • in February 2020 infections rose in the Italian towns of Bergamo and Lodi.
    • Lodi closed schools and businesses and made people stay at home within 3 days of the first infection.
    • Bergamo did the same only after 16 days, and had many more infections.
  • Science in society
    • scientific understanding is applied across societies to solve real-life problems such as disease control.

Section 3 of 7Hygiene

  • Hand washing
    • washing with soap before eating and after using the toilet removes bacteria and viruses.
  • Clean water and sewage treatment
    • they prevent diseases such as cholera.
  • Food
    • cook it thoroughly and store it in a fridge, because low temperature slows bacterial growth.
  • Surgery
    • surgeons sterilise instruments and wear gloves to prevent infection during operations.
  • Semmelweis
    • in the 1840s he showed that doctors washing their hands greatly reduced deaths of mothers after childbirth, before germs were understood.

Section 4 of 7Antibiotics

  • Antibiotics = medicines that kill bacteria or stop them from growing, without harming human cells.
  • Penicillin
    • the first antibiotic, discovered by Alexander Fleming in 1928 from the mould Penicillium.
  • Uses
    • they treat bacterial infections such as tuberculosis and some throat infections.
  • Not for viruses
    • viruses lack the cell structures antibiotics attack and live inside our own cells.

Section 5 of 7Antibiotic resistance

  1. In a population of bacteria, a few carry a random change that makes them resistant.
  2. When an antibiotic is used, the non-resistant bacteria are killed.
  3. The resistant bacteria survive and reproduce.
  4. The population becomes resistant, which is natural selection.
  • Causes
    • using antibiotics when they are not needed, or not finishing the course, helps resistant strains spread.
  • Problem
    • resistant bacteria such as MRSA are very hard to treat, so doctors prescribe antibiotics only when necessary.

Section 6 of 7Vaccination

  1. A vaccine contains a weakened, dead or harmless part of a pathogen, which cannot cause the disease but carries antigens.
  2. The vaccine is injected.
  3. White blood cells detect the antigens and make specific antibodies.
  4. Some of these cells stay in the blood as memory cells.
  5. If the real pathogen later infects the body, memory cells recognise it and make antibodies very quickly, so the person does not become ill.
  • Immunity
    • this protection is called immunity.
  • History
    • Edward Jenner developed the first vaccine, against smallpox, in 1796.
    • Vaccination has eradicated smallpox and almost removed polio.
  • Side effects
    • a few people have side effects, but these are usually mild and much less harmful than the diseases prevented.

Section 7 of 7Herd immunity and comparing methods

  • Herd immunity = protection of a population when most people are vaccinated, so the pathogen finds it hard to spread.
    • It protects people who cannot be vaccinated, such as babies and people with weak immune systems.
MethodHow it worksLimitation
HygieneStops pathogens spreadingNeeds constant habits and clean water
AntibioticsKill bacteria after infectionUseless against viruses; resistance
VaccinesMake the body ready before infectionA new vaccine is needed for changing viruses such as influenza

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