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BIOLOGY · Stage 8 · Chapter 5: Respiration and the Respiratory System

Biology 5.9 Asthma — Respiratory Conditions and Treatments — Alhussan International Academy - Biology (Stages 7-9) Revision Notes & Topical Questions

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Biology 5.9 Asthma — Respiratory Conditions and Treatments — Alhussan International Academy — Biology (Stages 7–9) notes: Describe the causes, symptoms and treatments of asthma, relate them to the structure of the airways and show how scientific understanding developed.Asthma — a…

  • Not infectious
  • Family and allergy
  • Active lives
  • Without treatment
  • Sensitive airways
  • Common triggers

Section 1 of 7What is asthma

  • Asthma
    • a long-term (chronic) condition of the airways in which they are sensitive and become inflamed and narrow in response to triggers.
  • Frequency
    • around 8–9% of people worldwide have asthma.
  • Not infectious
    • it cannot be caught from another person, and it is not usually curable but can be controlled with treatment.
  • Family and allergy
    • it often runs in families and is more common in people with allergies such as hay fever or eczema.
  • Active lives
    • many people with asthma, including top sports stars, live healthy, active lives.

Section 2 of 7What happens in an asthma attack

  • Breathing
    • a person struggles to breathe in and out and cannot get enough oxygen or remove toxic carbon dioxide.
  • Muscles
    • the muscles around the airways to the lungs contract, making the tubes narrower so it is hard to move air in or out.
      • (discovered from 1892)
  • Lining
    • the linings of the bronchi swell and make extra mucus, making breathing even harder.
      • (discovered almost 100 years later)
  • Result
    • less air reaches the alveoli, so less oxygen reaches the blood.
  • Symptoms:
    • wheezing;
    • coughing at night which disturbs sleep;
    • shortness of breath;
    • a tight feeling in the chest;
    • difficulty breathing.
  • Without treatment
    • asthma may make it impossible to run, play or work.

Section 3 of 7Triggers

  • Sensitive airways
    • people with asthma have very sensitive airways triggered by environmental triggers.
  • Common triggers
    • pollen, smoking, infections, food allergies, stress, air pollution, exercise, medicines, mould, dust mites, pets and cold air.
  • Frequency of attacks
    • some people have attacks every day and others only a few times a year.
  • Avoidance
    • avoiding triggers, for example with allergen-proof bedding and no smoke, helps control asthma.

Section 4 of 7Treatment

TreatmentHow it worksWhen used
Reliever inhaler (such as salbutamol)Relaxes the muscles around the bronchi, so the airways open quicklyDuring an attack, or before exercise to stop the tubes reacting
Preventer inhaler (steroid)Reduces inflammation, making the airways less sensitive and attacks much less likelyEvery day, to prevent attacks
  • Relievers
    • they were the first modern asthma medicines.
  • Preventers
    • they were developed once doctors discovered that the airways also become inflamed in asthma.
  • Combination
    • using preventers and relievers together lets many people live healthy, active lives.

Section 5 of 7Getting medicines to the lungs

  • Problem
    • doctors needed to get medicines down to where they are needed, deep in the airways.
  • Inhalers
    • engineers designed inhalers, medical devices that work with natural breathing to deliver medicine deep into the airways.
    • The drug is a fine mist delivered directly to the lungs, so it works fast and a small dose is enough.
    • A spacer device helps children and others to breathe in the medicine.

Section 6 of 7Scientific understanding and application

  • History
    • the Ancient Greeks, Egyptians and Romans described asthma attacks, but doctors began to understand them only in the 1800s.
  • Medicines
    • effective medicines were not developed until doctors understood the causes.
  • Application
    • engineers applied scientific knowledge to design inhalers.

Section 7 of 7Other respiratory conditions

  • Bronchitis
    • inflammation of the bronchi causing a cough with mucus, often from infection or smoking.
  • Emphysema
    • destruction of the alveoli.
  • Lung cancer
    • uncontrolled cell growth, strongly linked to smoking.
  • Peak flow meter
    • it measures how fast a person can blow air out, and is lower in asthma when the airways are narrowed, so daily readings show how well treatment works.

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