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7.8Natural Selection

Continuing Evolution — AP BIOLOGY Revision Notes & Topical Questions

5 min read 8 parts Lesson 9 of 13 1 quiz

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Lesson summary

7.8 Continuing Evolution — Notes — AP Biology notes: Explain how evolution is an ongoing process in all living organisms.Continuing change — all species have evolved and continue to evolve as environments change; populations evolve today.Evidence — genomic changes over time, cont…

  • Antibiotic resistance
  • Horizontal gene transfer
  • Emergent disease
  • Generation time
  • Reassortment
  • Coevolution

Section 1 of 8Evolution is ongoing

1
Continuing change — all species have evolved and continue to evolve as environments change; populations evolve today.
2
Evidence — genomic changes over time, continuous change in the fossil record, evolution of resistance, and pathogens causing emergent diseases.
3
Genomes — mutations and genetic drift drive divergence, and greater differences indicate a more distant common ancestor.
4
Rate — depends on generation time, population size, mutation rate and strength of selection, so short-generation organisms evolve observably fast.
5
Humans — also continue to evolve, e.g. lactase persistence in some populations and sickle-cell allele frequency in malarial regions.

Section 2 of 8Resistance as natural selection

1
Antibiotic resistance — random mutations produce some resistant bacteria;
  • when an antibiotic is used, susceptible bacteria die while resistant ones survive and reproduce,
  • so resistance alleles increase.
  • Antibiotics select for resistance; they do not cause the mutation.
  • Selective pressure comes from both antibiotic use and the immune system.
2
Bacteria can also gain resistance genes by horizontal gene transfer (conjugation, transformation, transduction), speeding evolution.
3
MRSA demonstrates natural selection in action.
4
Pesticide and herbicide resistance — insects and weeds (e.g. resistance to DDT) evolve the same way under strong selection.
5
Chemotherapy resistance — cancer cells show increasing resistance through selection of resistant cell lines.
6
Full explanation — random mutation, selective pressure, greater survival and reproduction of resistant cells, and a rising frequency of resistance.

Section 3 of 8Why prokaryote evolution is so fast

1
Generation time — as short as 20 minutes, so many generations occur in a day.
2
Population size — enormous, so even rare mutations occur somewhere each day.
3
Haploid genomes — a new allele is expressed immediately with no dominant allele to mask it.
4
Gene transfer — a useful gene can move between unrelated species.
5
Extreme environments — adaptation to hot springs, salt lakes and deep-sea vents is far faster than in larger organisms.

Section 4 of 8Emerging pathogens and viruses

1
Viruses — high mutation rates and short generation times produce new variants that may evade immunity; flu and HIV genomes (often RNA) are copied with little error checking and huge numbers of particles are produced.
2
Selection — the host immune system and drugs favour variants that escape them, so new strains appear.
3
Seasonal flu — mutations alter antigens each year and make current vaccinations ineffective, so a new vaccine is needed each year.
4
Viral populations — one infected person holds many slightly different genomes,
  • and if a drug removes most of them any surviving variant becomes the ancestor of the next population.
5
Combination drug therapy — HIV treatment uses several drugs because a virus needs several separate mutations at once to survive, which is unlikely.
6
Reassortment — two influenza strains infecting the same cell can swap RNA segments, creating a combination to which people have little immunity.
7
Viruses evolve only as they replicate inside host cells, so widely spreading outbreaks give more chances for new variants (SARS-CoV-2 variants).
8
Coevolution — two species evolve in response to each other.

Section 5 of 8Evolution happening now

ExampleSelective pressureResultTime scaleResponse
Antibiotic-resistant bacteriaAntibioticsMRSAYearsCareful antibiotic use
Flu virusImmunityNew strainsYearlyNew vaccine each year
HIVDrugs, immune systemDrug resistanceMonthsCombination therapy
Pesticide-resistant insectsPesticidesResistant pestsYearsIntegrated pest management
Galápagos finchesDroughtBeak size changesOne generation—

Section 6 of 8More from the specification

1Evolutionary cladistics and phylogenetic trees
  • Evolutionary cladistics and phylogenetic trees aligning homologous DNA and protein sequences allows evolutionary biologists to construct rooted phylogenetic trees depicting shared ancestry.
2Habitat
  • The place where an organism lives.
3Protein
  • A long chain of amino acids containing carbon, hydrogen, oxygen and nitrogen.
4Genetic diversity
  • The range of alleles within a population.
5Phylogenetic tree
  • Diagram showing evolutionary relationships between species.
6Allopatric speciation
  • Speciation caused by geographical isolation.
7Punctuated equilibrium
  • Speciation in rapid bursts between long stable periods.
8Geographical barrier
  • A physical feature, such as a mountain or sea, separating populations.
9Sympatric speciation
  • Speciation in the same area without a geographical barrier.
10Speciation
  • The formation of new species.
11Extinction
  • Loss of every member of a species.
12Isolation
  • Separation of populations so that they cannot interbreed.
13Barrier
  • A structure that prevents pathogens from entering.
14Cladogram
  • Diagram showing branching pattern of relationships with no timescale.

Section 7 of 8Key terms

TermMeaning
Continuing evolutionongoing change in populations over generations
Antibiotic resistancebacterial ability to survive an antibiotic
MRSAmethicillin-resistant Staphylococcus aureus
Horizontal gene transfergene exchange between organisms other than by reproduction
Emergent diseasedisease newly appearing through pathogen evolution
Generation timetime between one generation and the next
Reassortmentswapping of RNA segments between virus strains
Coevolutiontwo species evolving in response to each other

Section 8 of 8Exam technique

1
Saying antibiotics or drugs cause the resistance mutation — resistance arises randomly and they select existing resistant individuals.
2
Thinking evolution stopped in the past — populations evolve today.
3
Saying individuals evolve resistance during their lifetime — populations change over generations.
4
Treating viruses as cells that evolve alone — they evolve only as they replicate inside hosts.

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