Theme D — Continuity and change
Theme D — Continuity and change — IB Biology SL Revision Notes & Topical Questions
5 min read 13 parts Lesson 1 of 14 Unit quiz
Curriculum Equation Key قوانين الرقم الهيدروجيني والاتزان الأيوني - pH & Acid-Base Equilibrium FormulasFast Exam Solution
pH = -log[H⁺] | pOH = -log[OH⁻] | pH + pOH = 14 | [H⁺][OH⁻] = 10⁻¹⁴
Word Equation & Conditions: الرقم الهيدروجيني = -لوغاريتم تركيز أيون الهيدروجين | pH + pOH = 14
Location & Specifications: الاتزان الأيوني، كيمياء 3 ثانوي، التحصيلي، و AP Chemistry.
Lesson summary
Theme D — Continuity and change — IB BIOLOGY SL notes: Link DNA replication, protein synthesis, mutation, cell division, osmosis, reproduction, homeostasis and ecosystem stability in Theme D.TranscriptionRNA polymerase binds and unwinds the DNA at the gene.Free RNA nucleotides pa…
- Template strand
- Daughter strand
- Anticodons
- Somatic mutation
- Germ-line mutation
- Predicting an effect
Part 1 of 11From gene to polypeptide
- Transcription
From gene to polypeptide
RNA polymerase binds and unwinds the DNA at the gene.
Free RNA nucleotides pair with the template strand and are joined into mRNA.
The mRNA leaves the nucleus through a nuclear pore.
Template strand
Template strand the DNA strand read in transcription, and the RNA made is complementary to it
Daughter strand
Daughter strand a newly built strand formed on a template in replication
Part 2 of 11Translation in order
1
The small ribosomal subunit binds to the mRNA.
2
The initiator tRNA pairs with the start codon AUG.
3
The large subunit joins.
4
A second tRNA pairs with the next codon.
5
A peptide bond links the two amino acids.
6
The ribosome moves on one codon and the process repeats.
7
At a stop codon the polypeptide is released.
- Anticodons
- tRNA anticodons pair with mRNA codons
Part 3 of 11Mutations
Somatic mutation
Somatic mutation a mutation in a body cell
- It is not passed to offspring but may cause cancer.
Germ-line mutation
- Germ-line mutation occurs in cells that form gametes, so it is inherited and may cause genetic disease
Predicting an effect
- Predicting an effect work out the likely effect of the base change on the polypeptide
Part 4 of 11Cell division
Mitosis
- Mitosis keeps the chromosome number and genetic identity of the cells
- New cells arise only by cell division.
- Chromosomes condense so they can be moved without tangling.
Meiosis
- Meiosis halves the chromosome number to make gametes
- Crossing over and random orientation create variation.
- Non-disjunction can cause abnormal chromosome numbers.
Part 5 of 11Osmosis
1Water movement
- Water movement in osmosis water moves across a partially permeable membrane, and aquaporins are water channel proteins
2Red blood cell
- Red blood cell shrinks in a hypertonic solution
3Percentage change in mass
- Percentage change in mass used in osmosis practicals because the pieces start with different masses
- If the graph crosses zero at 0.3 mol dm-3, that is the isotonic concentration.
4Plasmolysis
- Plasmolysis the membrane of a plant cell is pulled away from the wall
5Cells without walls
- Cells without walls transplant kidney cells in pure water would swell and burst
6Contractile vacuole
- Contractile vacuole an ATP inhibitor stops it, so the protist swells and may burst
7Hydration shell
- Hydration shell the oxygen of water faces a sodium ion
8Repeats
- Repeats more repeats reduce the standard error
Part 6 of 11Reproduction and inheritance
Asexual reproduction
Asexual reproduction genetically identical offspring from one parent without gametes
Germination
Germination the growth of a seed into a seedling once water, oxygen and a suitable temperature are available
Gametes
- Gametes haploid, and fertilisation restores the diploid number
- Each gamete carries only one allele of each gene.
Homozygous
Homozygous carrying two identical alleles, such as AA or aa
Part 7 of 11Homeostasis
1
After a long fast the glucose level is low.
2
Alpha cells of the pancreas detect this and secrete glucagon.
3
Liver cells break glycogen into glucose.
4
Glucose is released and the concentration returns to the set point.
Homeostasis
Glycogen
Glycogen a branched storage polysaccharide in liver and muscle cells
Type 2 diabetes
- Type 2 diabetes judging lifestyle against genetic causes needs data on both
Paradigm shift
Paradigm shift a major change in scientific thinking when new evidence overturns accepted ideas
Part 8 of 11Ecosystem stability
Ecosystem stability
Requirements for a stable ecosystem
- A supply of energy.
- Recycling of nutrients by detritivores such as termites, worms and slugs, and decomposers such as fungi and bacteria.
- Genetic diversity.
- A suitable climate.
Tipping point
- Tipping point deforestation reduces transpiration and rainfall, and the drier forest may become savanna
Keystone species
- Keystone species sea otters eat urchins, and urchins graze kelp
- Beavers create wetlands and elephants keep grassland open.
Mesocosm
Mesocosm a clear sealed container with water, substrate, producers, consumers and decomposers placed in the light
- Oxygen, pH and population sizes are monitored over weeks.
- A control keeps the test factor unchanged.
- Terrestrial layers are gravel, charcoal, moss or filter paper, and compost with mosses and ferns.
- Aquatic mesocosms use pond sediment, pond water, healthy plants and few water fleas or snails.
- Only primary consumers are included, and the IB policy allows animals only if there is no alternative.
Part 9 of 11Sustainability
Sustainability
Maximum sustainable yield
Maximum sustainable yield the largest harvest that can be taken repeatedly without shrinking the population
Sustainable farming
- Cover crops and small doses of fertiliser.
- Biological control, such as ladybirds eating aphids.
- GM crops and renewable energy.
Fertiliser
- Fertiliser expensive and energy-intensive, so its price tracks energy costs
Part 10 of 11Pollution and restoration
Eutrophication
- Eutrophication nutrients cause an algal bloom, light is blocked, decomposition uses oxygen, and a dead zone forms
Biomagnification
- DDT moves from crops to waterways, plankton, fish and birds, thinning eggshells, and is now banned except for malaria control.
- Methylmercury forms from mercury released by coal burning and gold mining, so tuna and swordfish are risky.
Plastics
- Plastics turtles mistake bags for jellyfish, albatross chicks are fed plastic, and UV and waves break plastic into microplastics
Restoration
- Reintroduce apex predators.
- Connect habitats with corridors.
- Limit human use.
- Use controlled grazing or burning and allow succession, as at Hinewai Reserve in New Zealand.
Peat bog
- Peat bog draining lets air in, so aerobic decomposers respire and release CO2
Part 11 of 11More from the specification
1
Replication fidelity in inherited genes
- Replication fidelity in inherited genes stable hydrogen bonds between nitrogenous base pairs ensure accurate copying of essential regulatory genes during meiosis.
2
Genetic code and triplet codons
- A DNA molecule stores genetic information as a sequence of nucleotide bases;
- each triplet of bases codes for a specific amino acid in a polypeptide chain.
3
Transcription stage of protein synthesis
- During transcription in the nucleus, RNA polymerase synthesizes a complementary messenger RNA (mRNA) molecule using the DNA template strand.
4
Translation stage at the ribosome
- In the cytoplasm, the mRNA molecule binds to a ribosome where transfer RNA (tRNA) molecules with complementary anticodons deliver specific amino acids to assemble the polypeptide chain during translation.
5
Gene mutations and sickle cell anaemia
- A single base substitution mutation in the beta-globin gene (GAG to GTG) changes the codon and replaces hydrophilic glutamic acid with hydrophobic valine,
- causing sickle cell anaemia and haemoglobin aggregation.
6
Hydrogen bond
- The bond between paired bases that holds the two strands together.
7
Coding strand
- The DNA strand with the same base sequence as the mRNA (T for U).
8
Nuclear envelope
- The double membrane around the nucleus, with pores.
9
Translation
- Using the mRNA code to build a protein.
10
Sequence
- The order of bases in DNA or amino acids in a protein.
11
Triplet
- Three consecutive DNA bases that code for one amino acid.
12
Cytoplasm
- The jelly in which the cell's chemical reactions happen.
Key terms
| Term | Meaning |
|---|---|
| Template strand | The DNA strand that is read in transcription. |
| Somatic mutation | A mutation in a body cell that is not inherited. |
| Plasmolysis | The pulling away of the cell membrane from the cell wall in a plant cell. |
| Glycogen | A branched storage polysaccharide in liver and muscle cells. |
| Paradigm shift | A major change in scientific thinking after new evidence overturns accepted ideas. |
| Maximum sustainable yield | The largest harvest that can be taken repeatedly without shrinking the population. |
Avoid these mistakes
1
Saying that mitosis halves the chromosome number — it keeps it, and meiosis halves it
2
Putting secondary consumers in a mesocosm — include only primary consumers
3
Saying that stable ecosystems do not change — they resist and recover from change
4
Saying a somatic mutation is inherited — only germ-line mutations are passed on
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