2.9.3Structure & Functions in Living Organisms
Kidney: Excretion and Osmoregulation — Edexcel International GCSE Biology 4BI1 Revision Notes & Topical Questions
5 min read 4 parts Lesson 17 of 21 Unit quiz
Part 1 of 4Functions of the Kidney

The kidneys are a pair of organs at the back of the abdomen that filter the blood continuously.
Excretion
- Kidneys remove urea, a toxic waste made in the liver from the breakdown of excess amino acids, from the blood.
Excess ions
- Salts present in more than the body needs are also removed in the urine, so the ion balance of the blood is controlled.
Osmoregulation
- This is the control of water and solute concentration in the blood, which is an example of homeostasis.
Urine
- The final product is urine, a solution of urea, excess ions and excess water that is stored in the bladder.
Part 2 of 4Why Water Balance Matters
Body cells and blood plasma are mostly water, and water moves in and out of cells by osmosis.
Why Water Balance Matters
Too much water
- Blood plasma becomes too dilute, so water enters cells by osmosis; they swell and may burst.
Too little water
- Blood plasma becomes too concentrated, so water leaves cells by osmosis;
- they shrink and may be unable to work or die.
Stable conditions
- Keeping the blood concentration steady keeps the volume and function of cells steady.
Blood pressure
- The water content of the blood also affects the volume of blood and therefore blood pressure.
Part 3 of 4Water Gain and Loss
The kidneys adjust the only water loss that the body can control.
1
Water enters the body in food and drink, and a small amount is made inside cells during aerobic respiration.
2
Water leaves in exhaled air from the lungs, and this loss cannot be controlled directly.
3
Water also leaves in sweat from the skin, together with some ions and a little urea; this depends on temperature and exercise.
4
Water leaves in urine, and the volume of urine is changed by the kidneys to keep total body water steady.
5
On a hot day or after exercise, less water is lost in urine so that the body does not become dehydrated.
Part 4 of 4Exam Checklist & Tips
2.9.3 – Key Points for the Exam
- Excretion The removal of toxic waste products of metabolism and substances in excess from the body.
- Osmoregulation The control of the water and solute concentration of the blood.
- Homeostasis The maintenance of a constant internal environment.
- Urea A nitrogen-containing waste made in the liver from excess amino acids.
- Osmosis The movement of water across a partially permeable membrane from a dilute to a more concentrated solution.
Common Mistakes
- Saying that the kidneys make urea; urea is made in the liver and removed by the kidneys.
- Confusing excretion with egestion; egestion is the removal of undigested food as faeces.
- Stating that cells burst only when they lose water;
- losing water makes cells shrink, gaining too much makes them swell.
- Forgetting that the lungs and skin also lose water, but only kidney loss is regulated.
Last updated:
\n