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1.2Unit 1 — Cell Biology

Transport Across Cell Membranes

5 min read 5 parts Lesson 5 of 28 Virtual lab

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Part 1 of 3Structure of the cell membrane

Cell Membrane — 3D Fluid Mosaic (Step-by-Step)
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phospholipid structure
Phospholipid Bilayer
fluid mosaic model of cell membrane
Sodium channel open and closed in phospholipid bilayer
cell membrane
Evolution of Cell Membrane Models — Animated Simulation
Simple diffusion across a membrane
Cutaway of a lysosome showing membrane, enzymes and transport proteins
The Cell Membrane — v7.2 Engine X teaching console
  • Fluid Mosaic Model:
    • Composed of a phospholipid bilayer with protein molecules embedded throughout.
    • Phospholipids are fluid and move laterally, giving flexibility to the membrane.
    • The cell membrane is selectively permeable: small soluble molecules (oxygen, carbon dioxide, water, glucose) pass through easily;
      • large insoluble molecules (starch, proteins) cannot pass without transport mechanisms.

Part 2 of 3Passive transport: Diffusion and Osmosis

Hypertonic, isotonic and hypotonic solutions: red blood cells
Plasmolysed Plant Cell
Red Blood Cells & Osmosis
a turgid plant cell
plant cell vacuole
r099-turgid-plant-cell
r098-plasmolysed-plant-cell
tonicity solutions
Membrane diffusion
Membrane diffusion
osmosis in a plant cell
Osmosis
osmosis across a membrane diagram
Diffusion across a membrane (higher to lower concentration)
Facilitated Diffusion
Osmosis
Water uptake by osmosis
Water uptake by osmosis
Water uptake by osmosis
Water uptake by osmosis
Osmosis across a partially permeable membrane
Osmosis — Partially Permeable Membrane Simulation
Osmosis across a cell membrane (sucrose can't cross)
Diffusion of solute across the cell membrane lipid bilayer over time
1Passive transport
Movement of substances down a concentration gradient (from higher to lower concentration) without requiring cellular energy (ATP).
  • DiffusionMovement of solute molecules (e.g. O2 entering cells, CO2 leaving cells) down a concentration gradient until equilibrium is reached.
  • OsmosisMovement of water molecules from an area of higher water concentration to an area of lower water concentration across a selectively permeable membrane.
2Effects of osmosis on cells
Solution TypeAnimal Cell (Red Blood Cell)Plant Cell
Higher water concentration (pure water / hypotonic)Water enters cell by osmosis; cell swells and bursts (lysis) (no cell wall).Water enters cell; vacuole swells; cytoplasm pushes against cell wall; cell becomes turgid (cell wall prevents bursting).
Equal water concentration (isotonic)No net water movement; cell shape and volume remain unchanged.No net water movement; cell volume remains unchanged.
Lower water concentration (concentrated salt/sugar solution / hypertonic)Water leaves cell by osmosis; cell shrinks / shrivels.Water leaves vacuole; cytoplasm pulls away from cell wall; cell becomes plasmolysed.

Part 3 of 3Active transport

Active Transport
Active Transport
Active Transport Across the Cell Membrane
Active Transport
Active Transport
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r097-active-transport
Active Transport
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carrier protein transport
Active transport: movement against concentration gradient (ATP)
Root hair cell structure
Plant Cell Wall Structure
plant cell wall structure
Transport in plants and humans
Water Transport in a Plant
Mineral Ions — Full 2D Simulation (Mg²⁺ & NO₃⁻)
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  • Active transport:
    • Movement of molecules or ions against the concentration gradient (from an area of lower concentration to higher concentration).
    • Requires membrane carrier proteins that actively pump molecules across.
    • Requires cellular energy in the form of ATP generated during cellular respiration.
    • Example
      • Sodium-potassium pump maintaining electrical nerve impulses;
        • plant root hair cells accumulating mineral ions from dilute soil water.

Key terms

TermMeaning
Selectively permeableA membrane property allowing only certain molecules to pass freely while blocking others.
OsmosisThe net diffusion of water molecules from higher to lower water concentration across a selectively permeable membrane.
TurgidA plant cell swollen with water so that the vacuole and cytoplasm press firmly against the rigid cell wall.
PlasmolysedA plant cell in which water loss causes the cytoplasm to shrink away from the cell wall.
Active transportThe movement of ions or molecules across a membrane against a concentration gradient requiring ATP.

Avoid these mistakes

Avoid these mistakes
Stating plant cells burst in pure water — plant cells never burst because their strong cellulose cell wall withstands high internal turgor pressure.
Forgetting to mention ATP when defining active transport — active transport always requires cellular energy (ATP) produced by respiration.
Try it in the virtual labBeetroot membrane permeability
Cambridge 9700 AS Biology Core Formula

Magnification Triangle & Unit Conversion

Formula: M = I / A  ⇔  A = I / M  ⇔  I = M × A

Units: 1 mm = 1,000 μm = 1,000,000 nm.
Rule: Convert Image size (ruler mm) to μm by ×1,000 before dividing by Actual size.

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