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Course: AQA A Level Biology 7402
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Curriculum

AQA A Level Biology 7402

1. Biological Molecules

0/102

2. Cell Structure

0/95

3. Exchange and Transport

0/98

4. Genetics, Variation and Interdependence

0/94

5. Energy Transfers In and Between Organisms (A Level only)

0/63

6. Organisms Respond to Changes in their Environments (A Level only)

0/93

7. Genetics, Populations, Evolution and Ecosystems (A Level only)

0/55

8. The Control of Gene Expression (A Level only)

0/72

9. Exam Guidance and Skills

0/38
Quiz

3.4.4 Epigenetics – Exam questions

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  • Questions count: 11
  • Passing grade: B+
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1.
Which best defines epigenetics?
Changes in DNA base sequence
Mutations in gametes
Protein folding
Heritable changes in gene expression without changes to base sequence
2.
Which statement best describes Epigenetics?
An undifferentiated cell that can divide and differentiate into specialised cell types.
Addition of methyl groups to cytosine bases in DNA, usually silencing the gene.
Heritable changes in gene expression that do not involve changes to the DNA base sequence.
A DNA sequence upstream of a gene where RNA polymerase and transcription factors bind.
3.
What is the effect of DNA methylation on a gene?
Usually activates it
Changes its base sequence
Usually silences it
Causes alternative splicing
4.
How does histone acetylation increase transcription?
Adds positive charge so DNA binds tightly
Reduces attraction between histones and DNA so chromatin loosens
Removes introns
Changes the base sequence
5.
In the lac operon, what happens when lactose is present?
Lactose binds the repressor, which leaves the operator
The repressor binds more tightly
RNA polymerase is inhibited
The regulator gene is deleted
6.
Alternative splicing allows:
One gene to produce several different proteins
Introns to be translated
DNA to be methylated
mRNA to leave the nucleus
7.
Which cells can form any cell type including placenta?
Multipotent
Pluripotent
Totipotent
Unipotent
8.
Which statement best describes Transcription factor?
A protein that binds to DNA near a gene and increases or decreases its transcription.
Addition of acetyl groups to histones, loosening chromatin and allowing transcription.
Heritable changes in gene expression that do not involve changes to the DNA base sequence.
Removal of introns and joining of exons in pre-mRNA to form mature mRNA.
9.
Which statement best describes Histone acetylation?
An undifferentiated cell that can divide and differentiate into specialised cell types.
Addition of acetyl groups to histones, loosening chromatin and allowing transcription.
Heritable changes in gene expression that do not involve changes to the DNA base sequence.
A protein that binds to DNA near a gene and increases or decreases its transcription.
10.
Which statement best describes Splicing?
Removal of introns and joining of exons in pre-mRNA to form mature mRNA.
Heritable changes in gene expression that do not involve changes to the DNA base sequence.
A group of prokaryotic genes under the control of one promoter and operator, transcribed together.
A protein that binds to DNA near a gene and increases or decreases its transcription.
11.

Epigenetic changes such as DNA methylation

change the base sequence
are mutations
delete genes
affect gene expression without changing the base sequence
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Part of 8. The Control of Gene Expression (A Level only) — see every lesson and quiz in this unit.
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