3.4.2Additional lessons
Nerve Impulses — IB Biology SL Revision Notes & Topical Questions
5 min read 6 parts Lesson 62 of 142
Curriculum Equation Key قوانين الرقم الهيدروجيني والاتزان الأيوني - pH & Acid-Base Equilibrium FormulasFast Exam Solution
pH = -log[H⁺] | pOH = -log[OH⁻] | pH + pOH = 14 | [H⁺][OH⁻] = 10⁻¹⁴
Word Equation & Conditions: الرقم الهيدروجيني = -لوغاريتم تركيز أيون الهيدروجين | pH + pOH = 14
Location & Specifications: الاتزان الأيوني، كيمياء 3 ثانوي، التحصيلي، و AP Chemistry.
Part 1 of 6Resting Potential
Sodium-potassium pump
- Sodium-potassium pump The pump uses ATP to move three sodium ions out of the axon for every two potassium ions moved in.
Potassium leakage
- Potassium leakage Potassium ions leak out through open channels, so the inside becomes negative relative to the outside.
Resting potential
- Resting potential The membrane potential of a neurone at rest is about −70 mV.
Polarised
- Polarised A membrane with a difference in charge across it is said to be polarised.
Gradients
- Gradients The pump creates concentration gradients for sodium and potassium across the membrane.
Part 2 of 6Action Potential
1
A stimulus opens some sodium channels; if the potential reaches the threshold of about −55 mV, voltage-gated sodium channels open.
2
Sodium ions rush in, so the membrane is depolarised and the inside reaches about +40 mV.
3
Sodium channels close and voltage-gated potassium channels open.
4
Potassium ions leave the axon, repolarising the membrane back towards the resting potential.
5
The membrane briefly overshoots, then the pump restores the resting potential.
Part 3 of 6Propagation
Propagation
Local currents
- Local currents Sodium entering at one point spreads to the next region and brings it to threshold.
One direction
- One direction The region just passed is in a refractory period, so the impulse moves forward only.
All or nothing
- All or nothing An action potential occurs fully if the threshold is reached, and not at all if it is not.
Myelination
- Myelination In myelinated axons the impulse jumps between nodes of Ranvier, which is much faster than in unmyelinated axons.
Part 4 of 6Speed of Conduction
Speed of Conduction
Myelinated
- Myelinated Impulses jump from one node of Ranvier to the next, which is called saltatory conduction.
Diameter
- Diameter A wider axon has less resistance to the flow of ions, so it conducts impulses faster.
Temperature
- Temperature Higher temperature increases the speed of conduction, up to the point where proteins are damaged.
Part 5 of 6Worked Example
Question
- An impulse travels 0.6 m along a myelinated axon in 8 ms.
- Calculate its speed in m s⁻¹.
- Convert time8 ms = 0.008 s.
- Speed = distance ÷ time = 0.6 ÷ 0.008 = 75 m s⁻¹.
Answer 75 m s⁻¹ (example data).
Part 6 of 6Exam Checklist & Tips
3.4.2 – Key Points for the Exam
- Resting potential The potential difference across the membrane of an unstimulated neurone.
- Depolarisation A change in the membrane potential to a less negative value.
- Repolarisation Return of the membrane potential to its resting value.
- Threshold The membrane potential that must be reached to trigger an action potential.
Common Mistakes
- Saying that the impulse is a flow of electrons along the axon, when it involves ions crossing the membrane.
- Mixing up depolarisation (sodium enters) with repolarisation (potassium leaves).
- Stating that a stronger stimulus makes a bigger action potential, when it changes the frequency.
- Forgetting that the pump needs ATP to restore the gradients.
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