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4.6.3Additional lessons

The Menstrual Cycle — IB Biology SL Revision Notes & Topical Questions

5 min read 5 parts Lesson 118 of 142

📚 IB Biology SL Hub / Topical Revision
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Curriculum Equation Key قوانين الرقم الهيدروجيني والاتزان الأيوني - pH & Acid-Base Equilibrium FormulasFast Exam Solution
pH = -log[H⁺] | pOH = -log[OH⁻] | pH + pOH = 14 | [H⁺][OH⁻] = 10⁻¹⁴
Word Equation & Conditions: الرقم الهيدروجيني = -لوغاريتم تركيز أيون الهيدروجين | pH + pOH = 14
Location & Specifications: الاتزان الأيوني، كيمياء 3 ثانوي، التحصيلي، و AP Chemistry.
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Section 1 of 5Phases of the Cycle

An average cycle lasts about 28 days, though cycle length varies between individuals.

1
Day 1 is the first day of menstruation, when the endometrium from the last cycle breaks down and is shed with some blood.
2
The pituitary gland releases FSH, which stimulates several follicles in the ovary to develop; each follicle contains a maturing egg cell.
3
Growing follicles secrete oestrogen, which rebuilds the endometrium and makes it thicker with a good blood supply.
4
A surge of LH triggers ovulation at about day 14, when a mature follicle releases its egg into the oviduct.
5
The empty follicle becomes the corpus luteum, which secretes progesterone, maintaining the thick endometrium ready for an embryo.
6
If no embryo implants, the corpus luteum degenerates, hormone levels fall and the cycle restarts with menstruation.

Section 2 of 5The Four Hormones

FSH
  • FSH Follicle-stimulating hormone, from the pituitary, stimulates follicle development in the ovary.
LH
  • LH Luteinising hormone, from the pituitary, triggers ovulation and the formation of the corpus luteum.
Oestrogen
  • Oestrogen Secreted by growing follicles, it repairs and thickens the endometrium and affects pituitary secretion.
Progesterone
  • Progesterone Secreted by the corpus luteum, it maintains the endometrium and inhibits FSH and LH release.
HormoneSourceMain effect
FSHPituitaryFollicle growth
LHPituitaryOvulation, corpus luteum
OestrogenFollicleEndometrium repair
ProgesteroneCorpus luteumMaintains endometrium

Section 3 of 5Feedback Control

Feedback Control
Early negative feedback
  • Early negative feedback Rising oestrogen early in the cycle at moderate levels inhibits FSH secretion,
    • which prevents too many follicles from maturing.
Positive feedback
  • Positive feedback When oestrogen reaches a high peak just before ovulation it stimulates pituitary release of LH and FSH, causing the LH surge.
After ovulation
  • After ovulation High progesterone and oestrogen from the corpus luteum inhibit FSH and LH, so no new follicles begin to develop.
Cycle reset
  • Cycle reset When the corpus luteum fails, progesterone falls, inhibition stops and FSH can rise to start new follicle growth.

Section 4 of 5Reading Hormone Graphs

Oestrogen peak
  • Oestrogen peak The first peak occurs shortly before ovulation, followed by a smaller second rise during the luteal phase.
LH surge
  • LH surge A sharp peak at about the middle of the cycle marks the trigger for ovulation.
Progesterone
  • Progesterone Levels are low until after ovulation, then rise to a peak and fall before menstruation.
Endometrium thickness
  • Endometrium thickness It is thinnest around menstruation and thickest in the days before the next one if no embryo implants.

Section 5 of 5Exam Checklist & Tips

4.6.3 – Key Points for the Exam

  • Ovulation Release of an egg from a mature follicle in the ovary.
  • Follicle Fluid-filled structure in the ovary that contains a developing egg.
  • Corpus luteum Structure formed from the empty follicle that secretes progesterone.
  • Endometrium The lining of the uterus that thickens to receive an embryo.
  • Negative feedback Process in which a change causes responses that reduce that change.

Common Mistakes

  • Saying that FSH and LH are made in the ovary; they come from the pituitary gland.
  • Stating ovulation occurs at the end of menstruation; it is about the middle of the cycle.
  • Claiming progesterone triggers ovulation; the LH surge does.
  • Confusing the corpus luteum with the follicle; the corpus luteum forms after ovulation.

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